Kuen Yong Lee

Summary

Affiliation: Hanyang University
Country: Korea

Publications

  1. doi request reprint The spacer arm length in cell-penetrating peptides influences chitosan/siRNA nanoparticle delivery for pulmonary inflammation treatment
    Eun Ju Jeong
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Nanoscale 7:20095-104. 2015
  2. ncbi request reprint Quantifying interactions between cell receptors and adhesion ligand-modified polymers in solution
    Kuen Yong Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, South Korea
    Macromol Biosci 8:140-5. 2008
  3. doi request reprint Sequential delivery of TAT-HSP27 and VEGF using microsphere/hydrogel hybrid systems for therapeutic angiogenesis
    Seung Hwa Shin
    Department of Bioengineering and Institute for Bioengineering and Biopharmaceutical Research, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 166:38-45. 2013
  4. doi request reprint Optical Imaging and Gene Therapy with Neuroblastoma-Targeting Polymeric Nanoparticles for Potential Theranostic Applications
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, 133 791, South Korea
    Small 12:1201-11. 2016
  5. doi request reprint Injectable microsphere/hydrogel hybrid system containing heat shock protein as therapy in a murine myocardial infarction model
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    J Drug Target 21:822-9. 2013
  6. doi request reprint The effect of spacer arm length of an adhesion ligand coupled to an alginate gel on the control of fibroblast phenotype
    Jae Won Lee
    Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea
    Biomaterials 31:5545-51. 2010
  7. doi request reprint Co-delivery of vascular endothelial growth factor and angiopoietin-1 using injectable microsphere/hydrogel hybrid systems for therapeutic angiogenesis
    Seung Hwa Shin
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Pharm Res 30:2157-65. 2013
  8. doi request reprint Active blood vessel formation in the ischemic hindlimb mouse model using a microsphere/hydrogel combination system
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, 133 791, Republic of Korea
    Pharm Res 27:767-74. 2010
  9. doi request reprint Facile control of porous structures of polymer microspheres using an osmotic agent for pulmonary delivery
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 146:61-7. 2010
  10. doi request reprint Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 137:196-202. 2009

Collaborators

  • Jae Won Lee
  • Byung Soo Kim
  • Yoon Jeong Park
  • Honghyun Park
  • Eun Ju Jeong
  • Sang Kyung Lee
  • Taiyoun Rhim
  • Seung Hwa Shin
  • Dong Gyun Ahn
  • Jagadish Beloor
  • Do Yoon Kim
  • Irfan Ullah
  • Hwi Kim
  • Eunkyeong Woo
  • Priti Kumar
  • Young Je Kwark
  • SoYeon Park
  • Yu Jin Oh
  • Dong Wook Lee
  • Won Ho Park
  • Byung Moo Min
  • Sang Woo Kim
  • Doyun Kim
  • Nahyun Kim
  • Jongkil Kim
  • Minyoung Cho
  • Kunho Chung
  • Moonhwan Choi
  • So Young Park
  • Eun Kyung Woo
  • Seung Hyun Kim
  • Yong Hee Kim
  • Kwang Suk Lim
  • Hye Yeong Nam
  • Chang Seon Choi
  • Minsun Park
  • Sung Hwa Kim
  • Andrew Jackson
  • Sung Wan Kim
  • Ho Joo Yoon
  • Sang Heon Kim
  • Ji Young Seo
  • Ko Eun Park
  • Hong Seok Ban
  • Wonchae Choe
  • Sun Woong Kang
  • Kyoung Soo Yun
  • David J Mooney
  • Lim Jeong

Detail Information

Publications35

  1. doi request reprint The spacer arm length in cell-penetrating peptides influences chitosan/siRNA nanoparticle delivery for pulmonary inflammation treatment
    Eun Ju Jeong
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Nanoscale 7:20095-104. 2015
    ..Chitosan derivatives modified with oligoarginine containing a spacer arm can be considered as potential delivery vehicles for various genes. ..
  2. ncbi request reprint Quantifying interactions between cell receptors and adhesion ligand-modified polymers in solution
    Kuen Yong Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, South Korea
    Macromol Biosci 8:140-5. 2008
    ....
  3. doi request reprint Sequential delivery of TAT-HSP27 and VEGF using microsphere/hydrogel hybrid systems for therapeutic angiogenesis
    Seung Hwa Shin
    Department of Bioengineering and Institute for Bioengineering and Biopharmaceutical Research, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 166:38-45. 2013
    ..This approach to controlling the sequential release behaviors of multiple drugs could be useful in the design of novel drug delivery systems for therapeutic angiogenesis...
  4. doi request reprint Optical Imaging and Gene Therapy with Neuroblastoma-Targeting Polymeric Nanoparticles for Potential Theranostic Applications
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, 133 791, South Korea
    Small 12:1201-11. 2016
    ..This approach to designing and tailoring of polymeric nanoparticles for targeted delivery may be useful in the development of multimodality systems for theranostic approaches. ..
  5. doi request reprint Injectable microsphere/hydrogel hybrid system containing heat shock protein as therapy in a murine myocardial infarction model
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    J Drug Target 21:822-9. 2013
    ..Local and sustained delivery of anti-apoptotic proteins such as HSP27 using a hybrid system may present a promising approach to the treatment of ischemic diseases...
  6. doi request reprint The effect of spacer arm length of an adhesion ligand coupled to an alginate gel on the control of fibroblast phenotype
    Jae Won Lee
    Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea
    Biomaterials 31:5545-51. 2010
    ..This approach to controlling cell phenotype using adhesion peptides with various spacer arm lengths could be useful for designing novel scaffolds in tissue engineering applications...
  7. doi request reprint Co-delivery of vascular endothelial growth factor and angiopoietin-1 using injectable microsphere/hydrogel hybrid systems for therapeutic angiogenesis
    Seung Hwa Shin
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Pharm Res 30:2157-65. 2013
    ....
  8. doi request reprint Active blood vessel formation in the ischemic hindlimb mouse model using a microsphere/hydrogel combination system
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, 133 791, Republic of Korea
    Pharm Res 27:767-74. 2010
    ....
  9. doi request reprint Facile control of porous structures of polymer microspheres using an osmotic agent for pulmonary delivery
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 146:61-7. 2010
    ..This approach to controlling porous structures of polymer microspheres could be useful to develop novel pulmonary drug delivery systems...
  10. doi request reprint Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 137:196-202. 2009
    ..This approach to controlling the release behavior of TAT-HSP27 using microsphere/hydrogel combination delivery systems may be useful for treating myocardial infarction in a minimally invasive manner...
  11. doi request reprint Preparation and characterization of nonaarginine-modified chitosan nanoparticles for siRNA delivery
    SoYeon Park
    Department of Bioengineering and Institute for Bioengineering and Biopharmaceutical Research, Hanyang University, Seoul 133 791, Republic of Korea
    Carbohydr Polym 92:57-62. 2013
    ..In conclusion, nonaarginine-modified chitosan should be considered a potential carrier for various gene delivery applications...
  12. doi request reprint Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model
    Yu Jin Oh
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 150:56-62. 2011
    ..This approach to controlling the porous structure of polymeric microparticles, as well as the release behavior of drugs from the microparticles, could have useful applications in the pulmonary delivery of many therapeutic drugs...
  13. doi request reprint Effect of spacer arm length between adhesion ligand and alginate hydrogel on stem cell differentiation
    Jae Won Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Carbohydr Polym 139:82-9. 2016
    ....
  14. doi request reprint Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery
    Dong Wook Lee
    Department of Bioengineering, College of Engineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 139:146-52. 2009
    ..Chitosan/PG nanoparticles were considered promising for siRNA delivery due to their low cytotoxicity and ability to transport siRNA into cells, which can effectively inhibit induction of targeting mRNA...
  15. doi request reprint Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA
    Jagadish Beloor
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Biomaterials 33:1640-50. 2012
    ..3 mg total siRNA/kg body weight could effectively regress advanced stage tumors. Our results establish the promise of ABP as a common systemic delivery platform for both siRNA and DNA therapeutics...
  16. doi request reprint T cell-specific siRNA delivery using antibody-conjugated chitosan nanoparticles
    Jangwook Lee
    Department of Bioengineering and Institute for Bioengineering and Biopharmaceutical Research, Hanyang University, Seoul 133 791, Republic of Korea
    Bioconjug Chem 23:1174-80. 2012
    ..This approach to introducing T cell-specific antibody to chitosan nanoparticles may find useful applications for the treatment of various infectious diseases. ..
  17. doi request reprint Local and sustained vascular endothelial growth factor delivery for angiogenesis using an injectable system
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Pharm Res 26:1739-44. 2009
    ..We hypothesize that a microsphere/hydrogel combination system could be useful for the local and sustained delivery of recombinant human vascular endothelial growth factor (rhVEGF) to enhance angiogenesis in vivo...
  18. doi request reprint Theranostic gas-generating nanoparticles for targeted ultrasound imaging and treatment of neuroblastoma
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 136 791, Republic of Korea
    J Control Release 223:197-206. 2016
    ....
  19. doi request reprint Theranostics: Optical Imaging and Gene Therapy with Neuroblastoma-Targeting Polymeric Nanoparticles for Potential Theranostic Applications (Small 9/2016)
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, 133 791, South Korea
    Small 12:1110. 2016
    ....
  20. doi request reprint Tuning the sphere-to-rod transition in the self-assembly of thermoresponsive polymer hybrids
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 136 791, Republic of Korea
    Colloids Surf B Biointerfaces 136:612-7. 2015
    ..This approach to controlling the structure of polymer micelles from nanoparticles to fibrous hydrogels may be useful in applications in drug delivery and tissue engineering. ..
  21. doi request reprint Injectable microsphere/hydrogel combination systems for localized protein delivery
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Macromol Biosci 9:671-6. 2009
    ..The mixing ratio of the components was the primary controlling parameter of the protein release. This approach could be useful for development of injectable and localized drug delivery systems...
  22. doi request reprint Shear-reversibly crosslinked alginate hydrogels for tissue engineering
    Honghyun Park
    Department of Bioengineering, College of Engineering, Hanyang University, Seoul 133 791, Republic of Korea
    Macromol Biosci 9:895-901. 2009
    ....
  23. doi request reprint Stress response of fibroblasts adherent to the surface of plasma-treated poly(lactic-co-glycolic acid) nanofiber matrices
    Honghyun Park
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Colloids Surf B Biointerfaces 77:90-5. 2010
    ..This approach to controlling the surface properties and regulating expression of a stress gene could be useful in the design of synthetic ECMs for many tissue engineering applications...
  24. ncbi request reprint Trileucine residues in a ligand-CPP-based siRNA delivery platform improve endosomal escape of siRNA
    Irfan Ullah
    a Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul, South Korea
    J Drug Target . 2016
    ..Interestingly <3 Leu or >3 Leu residues were not as effective, suggesting that 3 Leu residues are useful for enhancing cytoplasmic delivery of siRNA routed through endosomes...
  25. doi request reprint Magnetic field-responsive release of transforming growth factor beta 1 from heparin-modified alginate ferrogels
    Hwi Kim
    Department of Bioengineering, Hanyang University, Seoul 04763, Republic of Korea
    Carbohydr Polym 151:467-73. 2016
    ..Alginate-based ferrogels that release drugs in a controlled manner may therefore be useful in many biomedical applications. ..
  26. doi request reprint Doxorubicin-loaded alginate-g-poly(N-isopropylacrylamide) micelles for cancer imaging and therapy
    Dong Gyun Ahn
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    ACS Appl Mater Interfaces 6:22069-77. 2014
    ..This approach to designing and tailoring natural polymer-based systems to fabricate nanoparticles at human body temperature may provide a useful means for cancer imaging and therapy. ..
  27. doi request reprint Injectable hydrogels prepared from partially oxidized hyaluronate and glycol chitosan for chondrocyte encapsulation
    Do Yoon Kim
    Department of Bioengineering, Hanyang University, Seoul 04763, Republic of Korea
    Carbohydr Polym 157:1281-1287. 2017
    ..This system may be potentially useful as an injectable system in many tissue engineering applications, including cartilage regeneration...
  28. doi request reprint Dual peptide-presenting hydrogels for controlling the phenotype of PC12 cells
    Jae Won Lee
    Department of Bioengineering, Hanyang University, Seoul 04763, Republic of Korea
    Colloids Surf B Biointerfaces 152:36-41. 2017
    ..These results suggest that hydrogels presenting multiple adhesion ligands offer many useful applications in tissue engineering approaches...
  29. doi request reprint Interaction-tailored cell aggregates in alginate hydrogels for enhanced chondrogenic differentiation
    Honghyun Park
    Department of Bioengineering, Hanyang University, Seoul, 04763, Republic of Korea
    J Biomed Mater Res A 105:42-50. 2017
    ..This approach may be useful to promote chondrogenesis with relatively few cells if they are encapsulated into a scaffold as a form of aggregates. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 42-50, 2017...
  30. doi request reprint The height of cell-adhesive nanoposts generated by block copolymer/surfactant complex systems influences the preosteoblast phenotype
    Eun Ju Jeong
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Colloids Surf B Biointerfaces 123:679-84. 2014
    ..This approach therefore holds great promise for the design of biomedical devices, as well as tissue engineering scaffolds...
  31. doi request reprint Ionically cross-linkable hyaluronate-based hydrogels for injectable cell delivery
    Honghyun Park
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    J Control Release 196:146-53. 2014
    ..This approach to the design and tailoring of ionically cross-linkable biomedical polymers may be broadly applicable to the development of biomaterials, especially in the drug delivery and tissue engineering fields. ..
  32. doi request reprint Cartilage regeneration using biodegradable oxidized alginate/hyaluronate hydrogels
    Honghyun Park
    Department of Bioengineering, Hanyang University, Seoul, 133 791, Republic of Korea
    J Biomed Mater Res A 102:4519-25. 2014
    ..These results indicate that dAL/HA hydrogels may be useful in cartilage regeneration, and in many tissue engineering applications...
  33. doi request reprint Shear reversible cell/microsphere aggregate as an injectable for tissue regeneration
    Eunkyeong Woo
    Department of Bioengineering, Hanyang University, Seoul, 133 791, Republic of Korea
    Macromol Biosci 14:740-8. 2014
    ..This cell/microsphere aggregate is useful to deliver chondrocytes into an animal model using a syringe, and effectively regenerates cartilage tissues in vivo. ..
  34. doi request reprint Electrospinning of polysaccharides for regenerative medicine
    Kuen Yong Lee
    Department of Bioengineering, Hanyang University, Seoul, South Korea
    Adv Drug Deliv Rev 61:1020-32. 2009
    ..The recent progress of nanofiber matrices electrospun from polysaccharides and their biomedical applications in tissue engineering, wound dressings, drug delivery, and enzyme immobilization are discussed...
  35. ncbi request reprint Regenerated silk fibroin nanofibers: water vapor-induced structural changes and their effects on the behavior of normal human cells
    Byung Moo Min
    Department of Oral Biochemistry and Craniomaxillofacial Reconstructive Science, Dental Research Institute, Seoul National University College of Dentistry, Seoul 110 749, South Korea
    Macromol Biosci 6:285-92. 2006
    ....