Research Topics

Genomes and Genes


Shanqun Jiang



  1. Jiang S, Pan M, Wu S, Venners S, Zhong G, Hsu Y, et al. Elevation in Total Homocysteine Levels in Chinese Patients With Essential Hypertension Treated With Antihypertensive Benazepril. Clin Appl Thromb Hemost. 2016;22:191-8 pubmed publisher
  2. Jiang S, Hsu Y, Venners S, Zhang Y, Xing H, Wang X, et al. Effects of protein coding polymorphisms in the kallikrein 1 gene on baseline blood pressure and antihypertensive response to irbesartan in Chinese hypertensive patients. J Hum Hypertens. 2011;25:327-33 pubmed publisher
    ..06), but DBP response did not differ. This study suggests that rs5516 in the KLK1 gene may be involved in the development of essential hypertension and in the regulation of SBP-lowering response to irbesartan in Chinese hypertensives. ..
  3. Jiang S, Chen Q, Venners S, Zhong G, Hsu Y, Xing H, et al. Effect of simvastatin on plasma homocysteine levels and its modification by MTHFR C677T polymorphism in Chinese patients with primary hyperlipidemia. Cardiovasc Ther. 2013;31:e27-33 pubmed publisher
    ..002) among patients with BMI ? 25 (kg/m(2) ). Simvastatin can cause a marked decrease in plasma Hcy levels. MTHFR C677T genetic variant contributes to simvastatin's effects among Chinese subjects with primary hyperlipidemia. ..