Thomas J McHugh

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. Weitemier A, McHugh T. Noradrenergic modulation of evoked dopamine release and pH shift in the mouse dorsal hippocampus and ventral striatum. Brain Res. 2017;1657:74-86 pubmed publisher
    ..We believe our findings hold implications for understanding the efficacy of α2 adrenergic agonists and antagonists that are used widely for therapeutic purposes. ..
  2. Boehringer R, Polygalov D, Huang A, Middleton S, Robert V, Wintzer M, et al. Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability. Neuron. 2017;94:642-655.e9 pubmed publisher
    ....
  3. McHugh T, Tonegawa S. CA3 NMDA receptors are required for the rapid formation of a salient contextual representation. Hippocampus. 2009;19:1153-8 pubmed publisher
    ..Our results suggest CA3 contributes both speed and salience to contextual processing and support the theory of competition between multimodal and unimodal conditioned stimuli for associative learning. ..

Locale

Detail Information

Publications3

  1. Weitemier A, McHugh T. Noradrenergic modulation of evoked dopamine release and pH shift in the mouse dorsal hippocampus and ventral striatum. Brain Res. 2017;1657:74-86 pubmed publisher
    ..We believe our findings hold implications for understanding the efficacy of α2 adrenergic agonists and antagonists that are used widely for therapeutic purposes. ..
  2. Boehringer R, Polygalov D, Huang A, Middleton S, Robert V, Wintzer M, et al. Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability. Neuron. 2017;94:642-655.e9 pubmed publisher
    ....
  3. McHugh T, Tonegawa S. CA3 NMDA receptors are required for the rapid formation of a salient contextual representation. Hippocampus. 2009;19:1153-8 pubmed publisher
    ..Our results suggest CA3 contributes both speed and salience to contextual processing and support the theory of competition between multimodal and unimodal conditioned stimuli for associative learning. ..