Thomas J McHugh
Affiliation: RIKEN Brain Science Institute
Chinnakkaruppan A, Wintzer M, McHugh T, Rosenblum K. Differential contribution of hippocampal subfields to components of associative taste learning. J Neurosci. 2014;34:11007-15 pubmed publisher
..Together, these data establish that the hippocampus is involved in associative taste learning and suggest an episodic component to this type of memory. ..
Chiang M, Huang A, Wintzer M, Ohshima T, McHugh T. A role for CA3 in social recognition memory. Behav Brain Res. 2018;: pubmed publisher
..These findings demonstrated CA3 pyramidal cell plasticity and transmission contribute to the encoding of social stimuli and help further identify the distinct circuits underlying the role of the hippocampus in social memory. ..
Weitemier A, McHugh T. Noradrenergic modulation of evoked dopamine release and pH shift in the mouse dorsal hippocampus and ventral striatum. Brain Res. 2017;1657:74-86 pubmed publisher
..We believe our findings hold implications for understanding the efficacy of ?2 adrenergic agonists and antagonists that are used widely for therapeutic purposes. ..
Boehringer R, Polygalov D, Huang A, Middleton S, Robert V, Wintzer M, et al
. Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability. Neuron. 2017;94:642-655.e9 pubmed publisher
McHugh T, Tonegawa S. CA3 NMDA receptors are required for the rapid formation of a salient contextual representation. Hippocampus. 2009;19:1153-8 pubmed publisher
..Our results suggest CA3 contributes both speed and salience to contextual processing and support the theory of competition between multimodal and unimodal conditioned stimuli for associative learning. ..