Takashi Shinohara

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. Kanatsu Shinohara M, Morimoto H, Shinohara T. Enrichment of Mouse Spermatogonial Stem Cells by the Stem Cell Dye CDy1. Biol Reprod. 2016;94:13 pubmed publisher
    ..Thus, CDy1 staining will provide a useful strategy for the enrichment of SSCs and may be used in conjunction with other reagents for the enrichment of SSCs. ..
  2. Kanatsu Shinohara M, Morimoto H, Shinohara T. Fertility of Male Germline Stem Cells Following Spermatogonial Transplantation in Infertile Mouse Models. Biol Reprod. 2016;94:112 pubmed publisher
    ..Efficient offspring production using GS cells and spermatogonial transplantation will be useful for analyzing factors involved in male fertility. ..
  3. Morimoto H, Kanatsu Shinohara M, Shinohara T. ROS-Generating Oxidase Nox3 Regulates the Self-Renewal of Mouse Spermatogonial Stem Cells. Biol Reprod. 2015;92:147 pubmed publisher
    ..Our results suggest that self-renewal of SSCs is regulated by sequential activation of different Nox genes, and underscore the complexity of ROS regulation in the self-renewal division of SSCs. ..
  4. Tanaka T, Kanatsu Shinohara M, Lei Z, Rao C, Shinohara T. The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells. Stem Cell Reports. 2016;7:279-91 pubmed publisher
    ..WNT5A promoted SSC activity both in vitro and in vivo. Therefore, FSH is not responsible for GDNF regulation, while LH negatively regulates SSC self-renewal by suppressing WNT5A via testosterone. ..

Detail Information

Publications4

  1. Kanatsu Shinohara M, Morimoto H, Shinohara T. Enrichment of Mouse Spermatogonial Stem Cells by the Stem Cell Dye CDy1. Biol Reprod. 2016;94:13 pubmed publisher
    ..Thus, CDy1 staining will provide a useful strategy for the enrichment of SSCs and may be used in conjunction with other reagents for the enrichment of SSCs. ..
  2. Kanatsu Shinohara M, Morimoto H, Shinohara T. Fertility of Male Germline Stem Cells Following Spermatogonial Transplantation in Infertile Mouse Models. Biol Reprod. 2016;94:112 pubmed publisher
    ..Efficient offspring production using GS cells and spermatogonial transplantation will be useful for analyzing factors involved in male fertility. ..
  3. Morimoto H, Kanatsu Shinohara M, Shinohara T. ROS-Generating Oxidase Nox3 Regulates the Self-Renewal of Mouse Spermatogonial Stem Cells. Biol Reprod. 2015;92:147 pubmed publisher
    ..Our results suggest that self-renewal of SSCs is regulated by sequential activation of different Nox genes, and underscore the complexity of ROS regulation in the self-renewal division of SSCs. ..
  4. Tanaka T, Kanatsu Shinohara M, Lei Z, Rao C, Shinohara T. The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells. Stem Cell Reports. 2016;7:279-91 pubmed publisher
    ..WNT5A promoted SSC activity both in vitro and in vivo. Therefore, FSH is not responsible for GDNF regulation, while LH negatively regulates SSC self-renewal by suppressing WNT5A via testosterone. ..