Manabu Ikeda

Summary

Affiliation: Kumamoto University
Country: Japan

Publications

  1. doi request reprint Neurocognitive features in male patients with schizophrenia exhibiting serious violence: a case control study.
    Hiroko Kashiwagi
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Kumamoto Japan National Center of Neurology and Psychiatry, Ogawa Higashi, Kodaira, Tokyo Japan
    Ann Gen Psychiatry 14:46. 2015
  2. doi request reprint Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled, confirmatory phase III trial.
    Manabu Ikeda
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Chuo Ku, Kumamoto 860 8556 Japan
    Alzheimers Res Ther 7:4. 2015
  3. doi request reprint Long-term donepezil use for dementia with Lewy bodies: results from an open-label extension of Phase III trial.
    Etsuro Mori
    Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai, Miyagi 980 8575 Japan
    Alzheimers Res Ther 7:5. 2015
  4. ncbi request reprint The uniqueness of Gogi aphasia owing to temporal lobar atrophy
    Hirotaka Tanabe
    Department of Neuropsychiatry, Neuroscience, Ehime University, Graduate School of Medicine, Shitsukawa, Toon shi, Ehime, Japan
    Alzheimer Dis Assoc Disord 21:S12-3. 2007
  5. ncbi request reprint Caregiver burden associated with behavioral and psychological symptoms of dementia in elderly people in the local community
    Naomi Matsumoto
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 23:219-24. 2007
  6. ncbi request reprint Frequency and clinical characteristics of early-onset dementia in consecutive patients in a memory clinic
    Shunichiro Shinagawa
    Department of Neuropsychiatry, Neuroscience, Ehime University, Graduate School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 24:42-7. 2007
  7. doi request reprint Clinical profiles of late-onset semantic dementia, compared with early-onset semantic dementia and late-onset Alzheimer's disease
    Hideaki Shimizu
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Shitsukawa, Japan
    Psychogeriatrics 11:46-53. 2011
  8. ncbi request reprint Comparison of behavioral and psychological symptoms in early-onset and late-onset Alzheimer's disease
    Yasutaka Toyota
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Ehime, Japan
    Int J Geriatr Psychiatry 22:896-901. 2007
  9. doi request reprint Transition of distinctive symptoms of semantic dementia during longitudinal clinical observation
    Tetsuo Kashibayashi
    Department of Neuropsychiatry, Ehime University Graduate School of Medicine, Toon, Japan
    Dement Geriatr Cogn Disord 29:224-32. 2010
  10. doi request reprint Efficacy of increasing donepezil in mild to moderate Alzheimer's disease patients who show a diminished response to 5 mg donepezil: a preliminary study
    Yusuke Yatabe
    Department of Neuropsychiatry, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 1 1 1 Honjo, Chuou ku, Kumamoto, Japan
    Psychogeriatrics 13:88-93. 2013

Collaborators

Detail Information

Publications64

  1. doi request reprint Neurocognitive features in male patients with schizophrenia exhibiting serious violence: a case control study.
    Hiroko Kashiwagi
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Kumamoto Japan National Center of Neurology and Psychiatry, Ogawa Higashi, Kodaira, Tokyo Japan
    Ann Gen Psychiatry 14:46. 2015
    ..Patient with violent or non-violent schizophrenia have distinct neuropsychological profiles. These results may help develop improved psychosocial treatments...
  2. doi request reprint Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled, confirmatory phase III trial.
    Manabu Ikeda
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Chuo Ku, Kumamoto 860 8556 Japan
    Alzheimers Res Ther 7:4. 2015
    ..With careful attention on gastrointestinal or parkinsonian symptoms, patients with DLB can safely benefit from treatment with donepezil. ClinicalTrials.gov Identifier: NCT01278407 (trial registration date: 14 January 2011)...
  3. doi request reprint Long-term donepezil use for dementia with Lewy bodies: results from an open-label extension of Phase III trial.
    Etsuro Mori
    Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai, Miyagi 980 8575 Japan
    Alzheimers Res Ther 7:5. 2015
    ..NCT01278407. Trial registration date: January 14, 2011...
  4. ncbi request reprint The uniqueness of Gogi aphasia owing to temporal lobar atrophy
    Hirotaka Tanabe
    Department of Neuropsychiatry, Neuroscience, Ehime University, Graduate School of Medicine, Shitsukawa, Toon shi, Ehime, Japan
    Alzheimer Dis Assoc Disord 21:S12-3. 2007
    ..In this brief historical report, Gogi aphasia is described and compared with the corresponding disorder called semantic dementia...
  5. ncbi request reprint Caregiver burden associated with behavioral and psychological symptoms of dementia in elderly people in the local community
    Naomi Matsumoto
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 23:219-24. 2007
    ..Despite many studies about the association between caregiver burden and behavioral and psychological symptoms of dementia (BPSD), there have been no population-based studies to evaluate caregiver burden associated with each BPSD...
  6. ncbi request reprint Frequency and clinical characteristics of early-onset dementia in consecutive patients in a memory clinic
    Shunichiro Shinagawa
    Department of Neuropsychiatry, Neuroscience, Ehime University, Graduate School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 24:42-7. 2007
    ..To investigate the frequency, rate of causes of dementia, and clinical characteristics of early-onset dementia in consecutive patients of a memory clinic...
  7. doi request reprint Clinical profiles of late-onset semantic dementia, compared with early-onset semantic dementia and late-onset Alzheimer's disease
    Hideaki Shimizu
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Shitsukawa, Japan
    Psychogeriatrics 11:46-53. 2011
    ....
  8. ncbi request reprint Comparison of behavioral and psychological symptoms in early-onset and late-onset Alzheimer's disease
    Yasutaka Toyota
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Ehime, Japan
    Int J Geriatr Psychiatry 22:896-901. 2007
    ..However, there have been very few reports about the differences in behavioral and psychological symptoms between these two groups...
  9. doi request reprint Transition of distinctive symptoms of semantic dementia during longitudinal clinical observation
    Tetsuo Kashibayashi
    Department of Neuropsychiatry, Ehime University Graduate School of Medicine, Toon, Japan
    Dement Geriatr Cogn Disord 29:224-32. 2010
    ..The aim of this study is to examine the clinical symptoms in a number of semantic dementia (SD) patients and to reveal the longitudinal progression and clinical course of these distinctive symptoms of SD...
  10. doi request reprint Efficacy of increasing donepezil in mild to moderate Alzheimer's disease patients who show a diminished response to 5 mg donepezil: a preliminary study
    Yusuke Yatabe
    Department of Neuropsychiatry, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 1 1 1 Honjo, Chuou ku, Kumamoto, Japan
    Psychogeriatrics 13:88-93. 2013
    ..The efficacy and safety of increasing the dose of donepezil to 10 mg daily were assessed in an open-label study of patients with mild to moderate Alzheimer's disease who were showing a diminished response to 5 mg daily...
  11. doi request reprint The usefulness of monitoring sleep talking for the diagnosis of Dementia with Lewy bodies
    Kazuki Honda
    Department of Neuropsychiatry, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
    Int Psychogeriatr 25:851-8. 2013
    ..It is frequently difficult to differentiate DLB from Alzheimer's disease (AD) and other types of dementia. This study examined the usefulness of monitoring sleep talking for the diagnosis of DLB...
  12. doi request reprint Risk of progression from mild memory impairment to clinically diagnosable Alzheimer's disease in a Japanese community (from the Nakayama Study)
    Naomi Sonobe
    Department of Neuropsychiatry, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan
    Int Psychogeriatr 23:772-9. 2011
    ....
  13. doi request reprint Cognitive function and psychiatric symptoms in early- and late-onset frontotemporal dementia
    Shunichiro Shinagawa
    Department of Neuropsychiatry, Neruoscience, Ehime University Graduate School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 25:439-44. 2008
    ..The aim of this study was to compare cognitive function and psychiatric symptoms in patients with early- and late-onset FTD...
  14. doi request reprint Two cases of frontotemporal dementia with predominant temporal lobe atrophy
    Hideaki Shimizu
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan
    Psychogeriatrics 9:204-7. 2009
    ..We suggest that clinical symptoms are the most important cues for an accurate clinical diagnosis and there is no exclusive relationship between the syndrome and atrophy of the temporal lobes...
  15. doi request reprint Long-term safety and efficacy of donepezil in patients with dementia with Lewy bodies: results from a 52-week, open-label, multicenter extension study
    Manabu Ikeda
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Dement Geriatr Cogn Disord 36:229-41. 2013
    ..To investigate the safety and efficacy of long-term administration (52 weeks) of donepezil in patients with dementia with Lewy bodies (DLB)...
  16. doi request reprint Association of cerebral small vessel disease with delusions in patients with Alzheimer's disease
    Yusuke Ogawa
    Department of Psychiatry and Neuropathobiology, Graduate School of Medical Science, Kumamoto University, Japan
    Int J Geriatr Psychiatry 28:18-25. 2013
    ..This study examined the association of SVD as observed on magnetic resonance imaging (MRI) with behavioural and psychological symptoms of dementia and cognitive function of patients with probable AD...
  17. doi request reprint Relationship between dementia severity and behavioural and psychological symptoms in early-onset Alzheimer's disease
    Hibiki Tanaka
    Department of Neuropsychiatry, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
    Psychogeriatrics 15:242-7. 2015
    ..We used a combination of community-based and hospital-based approaches to investigate the relationship between dementia severity and BPSD in EOAD patients...
  18. ncbi request reprint Initial symptoms in frontotemporal dementia and semantic dementia compared with Alzheimer's disease
    Shunichiro Shinagawa
    Department of Neuropsychiatry, Ehime University School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 21:74-80. 2006
    ....
  19. ncbi request reprint A longitudinal study regarding conversion from mild memory impairment to dementia in a Japanese community
    Tomohisa Ishikawa
    Department of Neuropsychiatry, Ehime University School of Medicine, Japan
    Int J Geriatr Psychiatry 21:134-9. 2006
    ..To estimate the rate that subjects with Mild Memory Impairment /Not Dementia (MMI/ND) shifted to dementia in a population-based cohort and to establish simple diagnostic methods for identification of high-risk persons for dementia...
  20. pmc Diagnosis of dementia with Lewy bodies: can 123I-IMP and 123I-MIBG scintigraphy yield new core features?
    Fumi Sakamoto
    1 Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan
    Br J Radiol 90:20160156. 2017
    ..The aim of this study was to evaluate whether nuclear medicine imaging findings may yield core features to be added to the diagnosis of DLB...
  21. doi request reprint Mental health among younger and older caregivers of dementia patients
    Asuka Koyama
    Department of Neuropsychiatry, Kumamoto University, Kumamoto, Japan
    Psychogeriatrics . 2016
    ..We aimed to compare the mental health of dementia caregivers with that of community residents and to clarify factors related to mental health problems in younger and older caregivers...
  22. pmc 123I-MIBG myocardial scintigraphy for the evaluation of Lewy body disease: are delayed images essential? Is visual assessment useful?
    Fumi Sakamoto
    1 Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan
    Br J Radiol . 2016
    ....
  23. ncbi request reprint [Content validity and inter-rater reliability of the Cognitive Fluctuation Inventory]
    Mamoru Hashimoto
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University
    Brain Nerve 66:175-83. 2014
    ..The objective of this study was to assess the content validity and inter-rater reliability of the CFI...
  24. ncbi request reprint [Validity and reliability of the Japanese version of the Neuropsychiatric Inventory Caregiver Distress Scale (NPI D) and the Neuropsychiatric Inventory Brief Questionnaire Form (NPI-Q)]
    Naomi Matsumoto
    Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Shitsukawa, Toon shi, Ehime 791 0295, Japan
    No To Shinkei 58:785-90. 2006
    ..We translated the NPI-Caregiver Distress Scale part of NPI (NPI-D) and NPI-Brief Questionnaire Form (NPI-Q) into Japanese and examined their validity and reliability...
  25. ncbi request reprint Efficacy of fluvoxamine as a treatment for behavioral symptoms in frontotemporal lobar degeneration patients
    Manabu Ikeda
    Department of Neuropsychiatry, Ehime University School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 17:117-21. 2004
    ..The behavioral symptoms, especially stereotyped behaviors of FTLD, significantly improved after treatment. Randomized, placebo- and other SSRI-controlled trials may improve available treatments...
  26. doi request reprint Comparisons of prevalence and related factors of depression in middle-aged adults between urban and rural populations in Japan
    Noboru Fujise
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University Graduate School of Medical Science, 1 1 1 Honjo, Chuo Ku, Kumamoto 860 8556, Japan Electronic address
    J Affect Disord 190:772-6. 2016
    ....
  27. ncbi request reprint Regional cerebral blood flow change in a case of Alzheimer's disease with musical hallucinations
    Takaaki Mori
    Department of Neuropsychiatry, Ehime University School of Medicine, Toon City, Ehime 791 0295, Japan
    Eur Arch Psychiatry Clin Neurosci 256:236-9. 2006
    ..In comparison with controls, the patient had increased rCBF in left temporal regions and left angular gyrus. This profile could be relevant to the neuroanatomical basis of musical hallucinations...
  28. doi request reprint Is sense of coherence helpful in coping with caregiver burden for dementia?
    Masateru Matsushita
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Psychogeriatrics 14:87-92. 2014
    ..In the present study, we examined the association between caregiver burden and SOC among caregivers to persons with dementia...
  29. doi request reprint Patient-related factors associated with depressive state in caregivers of patients with dementia at home
    Noriko Hasegawa
    Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan Department of Neuropsychiatry, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
    J Am Med Dir Assoc 15:371.e15-8. 2014
    ..To identify patient-related factors associated with depressive state in caregivers of patients with dementia, we investigated the caregivers' and patients' characteristics in relation to the depressive state in their caregivers...
  30. pmc Malnutrition in Alzheimer's Disease, Dementia with Lewy Bodies, and Frontotemporal Lobar Degeneration: Comparison Using Serum Albumin, Total Protein, and Hemoglobin Level
    Asuka Koyama
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    PLoS ONE 11:e0157053. 2016
    ..In conclusion, nutritional status was worse in patients with DLB and FTLD than in those with AD. A multidimensional approach, including blood testing, is needed to assess malnutrition in patients with dementia. ..
  31. doi request reprint Suicidal ideation and related factors among dementia patients
    Asuka Koyama
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan Electronic address
    J Affect Disord 178:66-70. 2015
    ..The present study examines 1) the sociodemographic and clinical features of dementia patients with suicidal ideation and 2) the effect of suicidal ideation on caregiver burden...
  32. doi request reprint Adequacy of Using Consensus Guidelines for Diagnosis of Dementia with Lewy Bodies in Clinical Trials for Drug Development
    Manabu Ikeda
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Dement Geriatr Cogn Disord 41:55-67. 2016
    ....
  33. doi request reprint Association between depression, examination-related stressors, and sense of coherence: the Ronin-Sei study
    Asuka Koyama
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Psychiatry Clin Neurosci 68:441-7. 2014
    ..These students are called ronin-sei. The purpose of this study was to clarify: (i) depression and somatic complaints in ronin-sei; and (ii) the association between depression, examination-related stressors, and sense of coherence (SOC)...
  34. doi request reprint Impact of donepezil hydrochloride on the care burden of family caregivers of patients with Alzheimer's disease
    Mamoru Hashimoto
    Department of Psychiatry and Neuropathobiology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Honjo, Kumamoto, Japan
    Psychogeriatrics 9:196-203. 2009
    ....
  35. doi request reprint Item non-response on self-reported depression screening questionnaire among community-dwelling elderly
    Asuka Koyama
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Chuo Ku, Kumamoto, Japan Electronic address
    J Affect Disord 162:30-3. 2014
    ....
  36. doi request reprint Sleep duration and its association with sleepiness and depression in "ronin-sei" preparatory school students
    Masateru Matsushita
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Kumamoto, Japan Electronic address
    Asian J Psychiatr 9:61-6. 2014
    ..We aimed to determine how sleep duration is associated with daytime sleepiness or depression in ronin-sei because impaired daytime performance is known to result from sleep deprivation...
  37. doi request reprint Living alone is associated with depression among the elderly in a rural community in Japan
    Ryuta Fukunaga
    Department of Psychiatry and Neuropathobiology, Kumamoto University Graduate School of Medical Science, Kumamoto, Japan
    Psychogeriatrics 12:179-85. 2012
    ..This study aimed to investigate factors associated with depression in a sample of elderly Japanese individuals in a rural community and to examine differences among factors associated with individuals living alone or living with others...
  38. ncbi request reprint Heterogeneity of cerebral blood flow in frontotemporal lobar degeneration and Alzheimer's disease
    Michinobu Nagao
    Department of Radiology, Matsuyama Medical Center for Cancer and Cardiovascular Disease, Matsuyama City, Ehime, Japan
    Eur J Nucl Med Mol Imaging 31:162-8. 2004
    ..7% and a specificity of 93.8%. Anterior FD and the ratio of anterior to posterior FD may be useful in distinguishing FTLD from AD...
  39. doi request reprint The relationship between post-stroke depression and physical recovery
    Shiho Matsuzaki
    Department of Neuropsychiatry, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
    J Affect Disord 176:56-60. 2015
    ..In this prospective study on the relationship between clinical PSD and physical recovery, we focused on (1) distinguishing between depression and apathy, (2) issues in assessment of PSD, and (3) timing of assessment...
  40. ncbi request reprint Delusions of Japanese patients with Alzheimer's disease
    Manabu Ikeda
    Department of Neuropsychiatry, Ehime University School of Medicine, Ehime, Japan
    Int J Geriatr Psychiatry 18:527-32. 2003
    ..Delusions constitute one of the most prominent psychiatric complications in Alzheimer's disease (AD). However, there is little consensus of the prevalence and associated factors for delusions in AD...
  41. pmc Relationship between eating disturbance and dementia severity in patients with Alzheimer's disease
    Kyoko Kai
    Department of Neuropsychiatry, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan Department of Psychiatry, Nozaki Hospital, Miyazaki, Japan
    PLoS ONE 10:e0133666. 2015
    ..The aims of this study were to investigate almost all eating disturbance and to examine the relationship of eating disturbance to dementia stage in AD...
  42. doi request reprint Comparing the driving behaviours of individuals with frontotemporal lobar degeneration and those with Alzheimer's disease
    Ryoko Fujito
    Department of Neuropsychiatry, Kochi Medical School, Kochi University, Kochi, Japan
    Psychogeriatrics 16:27-33. 2016
    ..Therefore, we compared the characteristics of driving behaviours in patients with FTLD and those with Alzheimer's disease (AD)...
  43. doi request reprint Effects of testosterone therapy on bipolar disorder with Klinefelter syndrome
    Kazuhiro Kawahara
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Gen Hosp Psychiatry 37:192.e1-2. 2015
    ..Testosterone therapy may prevent relapsing manic episodes of bipolar disorder in patients with KS...
  44. ncbi request reprint Epidemiology of frontotemporal lobar degeneration
    Manabu Ikeda
    Department of Neuropsychiatry, Ehime University School of Medicine, Ehime, Japan
    Dement Geriatr Cogn Disord 17:265-8. 2004
    ..Regarding the subtypes of FTLD, in Japan, compared with the data from the UK, FTD is less common, SD may be more common and PA is equally common. The reason for this discrepancy is supposed to be mainly based on the role of heredity...
  45. ncbi request reprint [How to make a differential diagnosis of the aphasic syndromes]
    Hirotaka Tanabe
    Department of Neuropsychiatry, Ehime University School of Medicine, Shitsukawa, Toon shi, Ehime 791 0295, Japan
    No To Shinkei 57:365-70. 2005
  46. ncbi request reprint [A case of motor neuron disease with progressive aphasia and dementia]
    Takayuki Hyodo
    Department of Neuropsychiatry, Ehime University School of Medicine, Shigenobu cho, Onsen gun, Ehime 791 0295, Japan
    No To Shinkei 54:713-8. 2002
    ..Her subsequent decline was rapid. It might be likely that aphasia is much more common in dementia with bulbar MND than is currently recognized because bulbar palsy might mask the language disorder...
  47. doi request reprint Face-specific memory deficits and changes in eye scanning patterns among patients with amnestic mild cognitive impairment
    Toshikazu Kawagoe
    Graduate School of Social and Cultural Sciences, Kumamoto University, Kumamoto, Japan
    Sci Rep 7:14344. 2017
    ..We demonstrate here the loss of short-term face memory in aMCI with abnormal scanning patterns that might reflect the cerebral abnormality found in patients with aMCI...
  48. doi request reprint Cross-cultural study of caregiver burden for Alzheimer's disease in Japan and Taiwan: result from Dementia Research in Kumamoto and Tainan (DeReKaT)
    Masateru Matsushita
    Center for Medical Education and Research, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Int Psychogeriatr 28:1125-32. 2016
    ..Caregiver burden (CB) of Alzheimer's disease (AD) in Taiwan is becoming an urgent social issue as well as that in Japan. The comparison of CB may explain how caregiver feels burden in each country...
  49. doi request reprint [Hirotaka Tanabe]
    Mamoru Hashimoto
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University
    Brain Nerve 66:1355-62. 2014
    ..In addition, he described in detail the behavioral symptoms of FTD. In his later years, he adovocated a neuropsychological approach to psychiatry...
  50. doi request reprint Family history of frontotemporal lobar degeneration in Asia--an international multi-center research
    Ryuji Fukuhara
    Department of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1 1 1, Honjo, Chuo Ku, Kumamoto City, Japan
    Int Psychogeriatr 26:1967-71. 2014
    ....
  51. pmc Diagnosis of dementia with Lewy bodies: diagnostic performance of combined ¹²³I-IMP brain perfusion SPECT and ¹²³I-MIBG myocardial scintigraphy
    Fumi Sakamoto
    Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, 1 1 1 Honjyo, Kumamoto, 860 0821, Japan
    Ann Nucl Med 28:203-11. 2014
    ..We assessed the value of combining (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy for the discrimination of dementia with Lewy bodies (DLB) from other types of dementia...
  52. doi request reprint Time course of the development of depressive mood and oppositional defiant behavior among boys with attention deficit hyperactivity disorder: differences between subtypes
    Hirokage Ushijima
    Department of Psychiatry and Neuropathobiology, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
    Psychiatry Clin Neurosci 66:285-91. 2012
    ....
  53. ncbi request reprint Interventional studies with the aim of reducing the burden of care through drug therapy of BPSD
    Manabu Ikeda
    Department of Neuropsychiatry, Ehime University School ofMedicine, Ehime, Japan
    Acta Neurol Taiwan 15:65-6. 2006
  54. ncbi request reprint [Dementia and driving: present status of drivers with dementia and response of their family's care in Japan]
    Naoto Kamimura
    Department of Neuropsychiatry, Kochi Medical School, 185 1 Kohasu, Oko cho, Nankoku Shi, Kochi 783 8505, Japan
    No To Shinkei 57:409-14. 2005
    ..Our study suggests that several important medical and social factors should be considered for the management of drivers with dementia. A consensus medical guideline for demented drivers has to be established...
  55. doi request reprint [White Matter Lesion and Alzheimer's Disease: The Association between Small Vessel Disease and Neuropsychiatric Symptoms in Alzheimer's Disease]
    Mamoru Hashimoto
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University
    Brain Nerve 67:427-32. 2015
    ..Our recent studies suggest that cerebral SVD observed on CT/MRI of patients with AD is associated with delusions and delirium as well as depression. Mechanisms underlying these psychiatric symptoms in patients with AD remain unclear. ..
  56. doi request reprint Clinical features of delusional jealousy in elderly patients with dementia
    Mamoru Hashimoto
    Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, Honjo1 1 1, Chuo Ku, Kumamoto, 860 8556, Japan
    J Clin Psychiatry 76:691-5. 2015
    ..The aim of the present study was to investigate the clinical features of delusional jealousy and possible mechanisms whereby delusional jealousy arises in patients with dementia...
  57. ncbi request reprint [The relationship between depression and dementia in elderly]
    Noboru Fujise
    Department of Psychiatry and Neuropathobiology, Faculty of Life Sciences, Kumamoto University
    Seishin Shinkeigaku Zasshi 114:276-82. 2012
    ..The underlying neuropathological condition that causes MCI or dementia might also cause depressive symptoms...
  58. ncbi request reprint [Care for the patients with frontotemporal lobar degeneration]
    Kazue Shigenobu
    Department of Neuropsychiatry, Asakayama General Hospital, 3 3 16 Imaike chou, Sakai ku, Sakai shi, Osaka 590 0013, Japan
    Brain Nerve 61:1337-42. 2009
    ....
  59. ncbi request reprint Positional candidate approach for the gene responsible for benign adult familial myoclonic epilepsy
    Akira Sano
    Department of Neuropsychiatry, Ehime University School of Medicine, Shigenobu, Onsen gun, Ehime, Japan
    Epilepsia 43:26-31. 2002
    ..2 and 3.5 kb. We analyzed the genomic sequence of the patients with BAFME and found no change in the pathogenesis of the disease...
  60. ncbi request reprint Reducing the burden of care in dementia through the amelioration of BPSD by drug therapy
    Manabu Ikeda
    Expert Rev Neurother 4:921-2. 2004
  61. ncbi request reprint [Symptomatology of aphasia]
    Hirotaka Tanabe
    Department of Neuropsychiatry, Ehime University School of Medicine
    Rinsho Shinkeigaku 44:837-8. 2004
    ..The table shows core symptoms of classical aphasic types. The figure presents a systematic approach to aphasia diagnosis based on several different patterns of aphasic output...
  62. ncbi request reprint [Pick complex]
    Yasutaka Toyota
    Department of Neuropsychiatry, Ehime University School of Medicine
    Nihon Rinsho 62:175-8. 2004
  63. ncbi request reprint Surface dyslexia in a Japanese patient with semantic dementia: evidence for similarity-based orthography-to-phonology translation
    Takao Fushimi
    Language, Cognition, Brain Science Research Group, Tokyo Metropolitan Institute of Gerontology, 35 2 Sakae cho, Itabashi ku, Tokyo 173 0015, Japan
    Neuropsychologia 41:1644-58. 2003
    ..Whichever of these interpretations is preferred, this study offers the most detailed information yet available on the characteristics of surface dyslexia in Japanese...
  64. ncbi request reprint Epidemiology and genetics of frontotemporal dementia/Pick's disease
    Thomas Bird
    VA Medical Center, Seattle, WA, USA
    Ann Neurol 54:S29-31. 2003