Takashi Sasayama

Summary

Affiliation: Kobe University
Country: Japan

Publications

  1. pmc Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy
    Noriaki Minami
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kusunoki cho 7 5 2, Chuo Ku, Kobe, Hyogo, 650 0017, Japan
    BMC Neurol 16:4. 2016
  2. pmc Cerebrospinal fluid interleukin-10 is a potentially useful biomarker in immunocompetent primary central nervous system lymphoma (PCNSL)
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    Neuro Oncol 14:368-80. 2012
  3. ncbi request reprint Trans-4-lodo,4'-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, 650 0017, Japan
    J Neurooncol 85:123-32. 2007
  4. doi request reprint Two metachronous tumors induced by radiation therapy: case report and review of the literature
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe, Japan
    J Neurooncol 88:315-20. 2008
  5. ncbi request reprint Glioblastoma multiforme associated with klinefelter syndrome
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo Japan
    Neurol Med Chir (Tokyo) 49:532-5. 2009
  6. doi request reprint MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, Japan
    Int J Cancer 125:1407-13. 2009
  7. doi request reprint Immunohistochemical and molecular genetics study of a granular cell astrocytoma: a case report of malignant transformation to a glioblastoma
    Taiji Ishii
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan
    Neuropathology 33:299-305. 2013
  8. doi request reprint MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells
    Hirotomo Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    J Neurooncol 111:273-83. 2013
  9. ncbi request reprint Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells
    Kazuhiro Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chou ku, Kobe, 650 0017, Japan
    J Neurooncol 84:233-44. 2007
  10. doi request reprint Myo-inositol concentration in MR spectroscopy for differentiating high grade glioma from primary central nervous system lymphoma
    Hiroaki Nagashima
    Department of Neurosurgery, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, 650 0017, Japan
    J Neurooncol . 2017

Collaborators

Detail Information

Publications44

  1. pmc Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy
    Noriaki Minami
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kusunoki cho 7 5 2, Chuo Ku, Kobe, Hyogo, 650 0017, Japan
    BMC Neurol 16:4. 2016
    ....
  2. pmc Cerebrospinal fluid interleukin-10 is a potentially useful biomarker in immunocompetent primary central nervous system lymphoma (PCNSL)
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    Neuro Oncol 14:368-80. 2012
    ..37; 95% confidence interval, 0.985-11.528; log-rank, P= .038). These results indicate that the CSF level of IL-10 may be a useful diagnostic and prognostic biomarker in patients with PCNSLs...
  3. ncbi request reprint Trans-4-lodo,4'-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, 650 0017, Japan
    J Neurooncol 85:123-32. 2007
    ..Therefore, we conclude that TLBC may be a potential chemotherapeutic agent for human glioma...
  4. doi request reprint Two metachronous tumors induced by radiation therapy: case report and review of the literature
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe, Japan
    J Neurooncol 88:315-20. 2008
    ..Whenever radiation is administered to children or young adults, careful serial screening studies are needed...
  5. ncbi request reprint Glioblastoma multiforme associated with klinefelter syndrome
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo Japan
    Neurol Med Chir (Tokyo) 49:532-5. 2009
    ..The abnormal genetic constitution of this patient may have been directly responsible for the poor outcome...
  6. doi request reprint MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, Japan
    Int J Cancer 125:1407-13. 2009
    ..Finally, multifocal lesions on enhanced MRI of 7 malignant gliomas were associated with higher expression levels of miR-10b (p = 0.02). Our data indicated that miR-10b might play some role in the invasion of glioma cells...
  7. doi request reprint Immunohistochemical and molecular genetics study of a granular cell astrocytoma: a case report of malignant transformation to a glioblastoma
    Taiji Ishii
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan
    Neuropathology 33:299-305. 2013
    ..The tumor progressed despite extensive chemotherapy, and the patient died 1 year after the initial treatment. Our immunohistochemical, genetic and chromosomal analyses indicate that the glioblastoma was transformed from the GCA...
  8. doi request reprint MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells
    Hirotomo Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    J Neurooncol 111:273-83. 2013
    ..These results suggest that miR-183 upregulation in malignant gliomas induces HIF-1α expression by targeting IDH2 and may play a role in glioma biology...
  9. ncbi request reprint Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells
    Kazuhiro Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chou ku, Kobe, 650 0017, Japan
    J Neurooncol 84:233-44. 2007
    ..05). These results suggest that rapamycin in combination with DNA-damaging agents may be efficacious in the treatment of malignant gliomas...
  10. doi request reprint Myo-inositol concentration in MR spectroscopy for differentiating high grade glioma from primary central nervous system lymphoma
    Hiroaki Nagashima
    Department of Neurosurgery, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, 650 0017, Japan
    J Neurooncol . 2017
    ..In conclusion, noninvasive analysis of mIns using single-voxel MRS may be useful in distinguishing gliomas from other brain tumors, particularly PCNSLs...
  11. doi request reprint Tumor-Associated Macrophages Associate with Cerebrospinal Fluid Interleukin-10 and Survival in Primary Central Nervous System Lymphoma (PCNSL)
    Takashi Sasayama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan
    Brain Pathol 26:479-87. 2016
    ..Our results indicate that a high level of IL-10 in CSF may be positively associated with the infiltration level of TAMs in PCNSLs. ..
  12. doi request reprint STAT3 activation is associated with cerebrospinal fluid interleukin-10 (IL-10) in primary central nervous system diffuse large B cell lymphoma
    Takashi Mizowaki
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, 650 0017, Japan
    J Neurooncol 124:165-74. 2015
    ..These results suggest that the STAT3 activity is correlated with CSF IL-10 level, which is a useful marker for STAT3 activity in PCNS DLBCLs. ..
  13. ncbi request reprint The novel VEGF receptor antagonist, VGA1155, reduces edema, decreases infarct and improves neurological function after stroke in rats
    Junji Koyama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe 650 0017, Japan
    Kobe J Med Sci 56:E1-11. 2010
    ..The data suggested that VGA1155 has antiedematous effect in acute phase after transient focal cerebral ischemia and improves neurological and histological outcomes 1 week after ischemic injury...
  14. doi request reprint Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports
    Hiroaki Nagashima
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan Electronic address
    World Neurosurg 104:1050.e7-1050.e11. 2017
    ..Here we describe a different pattern of MRS-based cerebral metabolism findings in patients with dAVF...
  15. doi request reprint Combined IDH1 mutation and MGMT methylation status on long-term survival of patients with cerebral low-grade glioma
    Kazuhiro Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan Electronic address
    Clin Neurol Neurosurg 138:37-44. 2015
    ..In particular, the importance of prognostic factors for survival remains a matter of discussion. The purpose of this study was to validate prognostic factors for survival in patients with LGG...
  16. pmc GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients
    Satoshi Nakamizo
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    J Neurooncol 113:65-74. 2013
    ..Our study suggests that the metabolomic analysis of CSF from glioma patients may be useful for predicting the glioma grade, metabolic state, and prognosis of gliomas...
  17. ncbi request reprint Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report
    Hirotomo Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo
    Neurol Med Chir (Tokyo) 50:689-93. 2010
    ..This case suggests that TMZ may be effective for brain metastasis of undifferentiated sarcoma without MGMT protein expression...
  18. ncbi request reprint Synthetic Smac peptide enhances the effect of etoposide-induced apoptosis in human glioblastoma cell lines
    Katsu Mizukawa
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Chuo Ku, Kobe, Japan
    J Neurooncol 77:247-55. 2006
    ..These results suggest that synthetic Smac peptide may be a new molecular targeting anti-tumor therapy for human glioblastoma...
  19. ncbi request reprint Anti-VEGF receptor antagonist (VGA1155) reduces infarction in rat permanent focal brain ischemia
    Yoshiyuki Chiba
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe 650 0017, Japan
    Kobe J Med Sci 54:E136-46. 2008
    ..We examined the therapeutic effect of VGA1155 (5- [N-Methyl-N- (4-octadecyloxyphenyl) acetyl] amino-2-methyl-thiobenzoic acid), a novel small molecule antagonist of VEGF, on rat permanent focal cerebral ischemia...
  20. doi request reprint Rapid regrowth of an atypical choroid plexus papilloma located in the cerebellopontine angle
    Kazuhiro Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan
    J Clin Neurosci 16:121-4. 2009
    ..Pathological examination again revealed increased mitotic activity and supported a diagnosis of atypical choroid plexus papilloma...
  21. ncbi request reprint Isolated oculomotor nerve paresis in anaplastic astrocytoma with exophytic invasion
    Kazuhiro Tanaka
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Japan
    Neurol Med Chir (Tokyo) 46:198-201. 2006
    ..The tumor was removed subtotally. The histological diagnosis was anaplastic astrocytoma. Malignant glioma with exophytic growth in the temporal lobe should be considered in the differential diagnosis of isolated oculomotor nerve paresis...
  22. doi request reprint [Two cases of cerebral infarction due to focal irradiation for glioma in adults]
    Noriaki Minami
    Department of Neurosurgery, Kobe University Graduate School of Medicine
    No Shinkei Geka 43:344-51. 2015
    ..Therefore, regular evaluation of intracranial vasculature following radiation therapy is necessary. ..
  23. ncbi request reprint Long-term survival after surgical resection of primary spinal malignant melanoma
    Masamitsu Nishihara
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo
    Neurol Med Chir (Tokyo) 49:546-8. 2009
    ..However, the clinical course is still unknown, and CNS dissemination is regarded fatal. The unusually long survival in the present case indicates the effectiveness of the combined radiotherapy and interferon therapy...
  24. doi request reprint Duplex-assisted carotid artery stenting without administration of contrast medium for patients with chronic kidney disease or allergic reaction
    Takashi Mizowaki
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, 650 0017, Japan
    Neuroradiology 58:679-86. 2016
    ..We aimed to investigate the safety and feasibility of duplex-assisted carotid artery stenting (CAS) without administration of contrast medium for the prevention of adverse reactions...
  25. ncbi request reprint Morbidity of stereotactic biopsy for intracranial lesions
    Masamitsu Nishihara
    Department of Neurosurgery, Nishi Kobe Medical Center, Kobe, Japan
    Kobe J Med Sci 56:E148-53. 2011
    ..36). The overall morbidity rate was 6.4% (37/575). We considered that tumors of the basal ganglia (putamen or globus pallidus), thalamus and glioma were risk factors of morbidity for CT-guided STB...
  26. ncbi request reprint Xanthogranuloma of the sellar region--case report
    Atsushi Arai
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
    Neurol Med Chir (Tokyo) 50:488-91. 2010
    ..Her visual symptoms recovered postoperatively although the hypopituitarism remained. Xanthogranuloma of the sellar region is rare, but must be considered in the differential diagnosis of tumors of the sellar region...
  27. pmc Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index
    Kazuyuki Uehara
    Division of Radiation Oncology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
    Radiat Oncol 7:104. 2012
    ....
  28. doi request reprint Supratentorial pure cortical ependymoma
    Satoshi Nakamizo
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    J Clin Neurosci 19:1453-5. 2012
    ..A diagnosis of ependymoma of World Health Organization grade II was made. The patient has not had a seizure since the operation. There has been no clinical or radiologic evidence of recurrence during a 16-month postoperative follow-up...
  29. doi request reprint A large cavernous malformation of the third ventricle floor: A case report
    Hiroaki Nagashima
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan Electronic address
    Neurol Neurochir Pol 49:446-50. 2015
    ..Despite its rarity, cavernous malformation should be suspected when a tumor is detected in the vicinity of the third ventricle floor. It is treatable through surgical resection. ..
  30. ncbi request reprint Rosette-forming glioneuronal tumor of the fourth ventricle--case report
    Atsushi Arai
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
    Neurol Med Chir (Tokyo) 50:224-8. 2010
    ..Surgical resection requires care to prevent major surgical morbidities associated with lesions invading the cerebellum or brainstem...
  31. doi request reprint Pediatric orbital schwannoma originating from the oculomotor nerve
    Hiroaki Nagashima
    Department of Neurosurgery, Hyogo Prefectural Kobe Children s Hospital, Kobe, Hyogo, Japan
    J Neurosurg Pediatr 9:165-8. 2012
    ..Despite the rarity of these intraorbital extraocular tumors in children, schwannomas should be differentiated from other intraorbital tumors...
  32. ncbi request reprint [The study of spinal abnormalities associated with cloacal exstrophy]
    Satoshi Nakamizo
    Department of Neurosurgery, Hyogo Prefectural Kobe Children s Hospital, Japan
    No Shinkei Geka 39:37-43. 2011
    ..All 4 patients with lipoma and/or thickened filum were asymptomatic. Two of them were conservatively treated, and they remain asymptomatic. Terminal myelocystocele and symptomatic syrinx should be surgically treated...
  33. doi request reprint Radiotherapy for brainstem gliomas in children and adults: A single-institution experience and literature review
    Kenji Yoshida
    Division of Radiation Oncology, Kobe University Graduate School of Medicine, Kobe, Japan
    Asia Pac J Clin Oncol . 2016
    ..To evaluate the treatment results of radiotherapy (RT) in children and adults with brainstem gliomas (BSGs) and review the previous literature...
  34. pmc Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma
    Hiroaki Nagashima
    Department of Neurosurgery, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, Japan H N, K T, T S, N S, K M, J S, Y Y, K H, E K Division of Evidence based Laboratory Medicine, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, Japan Y I, Y T Center for Radiology and Radiation Oncology, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, Japan K K Department of Diagnostic Pathology, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, Japan T I Division of Radiation Oncology, Kobe University Graduate School of Medicine and Kobe University Hospital, Kobe, Japan R S Department of Neurosurgery, University of Tokyo Hospital, Tokyo, Japan A M
    Neuro Oncol 18:1559-1568. 2016
    ..However, conventional MR spectroscopy (MRS)-based noninvasive detection of 2HG is challenging. In this study, we aimed to determine the additional value of other metabolites in predicting IDH1 mutations with conventional MRS...
  35. pmc Skull metastasis as initial manifestation of pulmonary epithelial-myoepithelial carcinoma: a case report of an unusual case
    Masamitsu Nishihara
    Department of Neurosurgery, Nishi Kobe Medical Center, Nishi ku, Kobe 651 2273, Japan
    Case Rep Oncol Med 2011:610383. 2011
    ..Pulmonary EMC was diagnosed. The MIB-1 index in primary lesion was approximately 10%. The skull and dura are possible sites for metastasis from pulmonary EMC. The MIB-1 index is a predictive marker of malignant potential...
  36. ncbi request reprint Epidermoid cyst in Meckel's cave with unusual computed tomography and magnetic resonance imaging findings. Case report
    Atsushi Arai
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan
    Neurol Med Chir (Tokyo) 50:701-4. 2010
    ....
  37. doi request reprint Rapid tumor growth with glial differentiation of central neurocytoma after stereotactic radiosurgery
    Hirotomo Tanaka
    Department of Neurosurgery, Hyogo Emergency Medical Center Kobe Red Cross Hospital, Chuo Ku, Kobe, Japan
    J Clin Neurosci 31:188-92. 2016
    ..Our case suggests that malignant transition with aberrant angiogenesis and glial differentiation may be attributable to SRS. ..
  38. ncbi request reprint Effect of VEGF receptor antagonist (VGA1155) on brain edema in the rat cold injury model
    Junji Koyama
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan
    Kobe J Med Sci 53:199-207. 2007
    ..Histological evaluation of brain lesion showed no significant reduction of damaged area 1 week after injury by VGA1155. The data suggest that VGA1155 may have antiedematous effect in acute phase after cold injury...
  39. doi request reprint Central neurocytoma with ependymoma-like glial component
    Fumi Kawakami
    Department of Diagnostic Pathology, Kobe University Hospital, 7 5 2, Kusunoki cho, Chuou ku, Kobe, Hyogo, 650 0017, Japan
    Brain Tumor Pathol 32:119-23. 2015
    ..The tumor location, infiltrating the corpus callosum, and histology were distinctive and might represent a peculiar subtype of glioneuronal tumor. ..
  40. doi request reprint Diagnostic Performance and Safety of Positron Emission Tomography Using 18F-Fluciclovine in Patients with Clinically Suspected High- or Low-grade Gliomas: A Multicenter Phase IIb Trial
    Toshihiko Wakabayashi
    Department of Neurosurgery, Nagoya University, Graduate School of Medicine, Aichi, Japan
    Asia Ocean J Nucl Med Biol 5:10-21. 2017
    ....
  41. pmc Different spatial distribution between germinal center B and non-germinal center B primary central nervous system lymphoma revealed by magnetic resonance group analysis
    Manabu Kinoshita
    Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka Japan M K, Y C, N K, N H, T Y Department of Neurosurgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan M K Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan T S, K T, E K Department of Neurosurgery and Neuro Oncology, National Cancer Center Hospital, Tokyo, Japan Y N, H A, Y O, M O, Y M, S S Division of Ultrahigh Field MRI, Iwate Medical University, Yahaba, Japan F Y Department of Biomedical Statistics and Bioinformatics, Kyoto University Hospital, Kyoto, Japan A K
    Neuro Oncol 16:728-34. 2014
    ..This research aimed to elucidate special distribution characteristics of primary central nervous system lymphoma (PCNSL) within the brain with respect to molecular marker expression patterns...
  42. ncbi request reprint Sca-1 and Thy-1 accelerate neuron-like differentiation in bone marrow stromal cells
    Takashi Mizobe
    Department of Neurosurgery, Kobe University Graduate School of Medicine
    Kobe J Med Sci 52:119-25. 2006
    ..Neuron-like differentiation of bone marrow cells can be enhanced by selection using cell surface proteins...
  43. ncbi request reprint Congenital cavernous angioma exhibits a progressive decrease in size after birth
    Shigeto Hayashi
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, 650 0017, Chuo Ku, Kobe, Japan
    Childs Nerv Syst 20:199-203. 2004
    ..There was no evidence of hemorrhage in the angioma on serial CT scans. The histopathology revealed thrombosis of cavernous vessels with hyaloid changes in the angioma...
  44. ncbi request reprint [Multidisciplinary treatment for severe syndromic craniosynostosis]
    Atsushi Uyama
    Department of Neurosurgery, Hyogo Prefectural Kobe Children s Hospital, 1 1 1 Takakuradai, Suma ku, Kobe shi, Hyogo 654 0081, Japan
    No Shinkei Geka 37:25-34. 2009
    ..Multidisciplinary therapy is essential for treating severe syndromic craniosynostosis due to systematic osseocartilaginous aplasia...