Affiliation: Japan Advanced Institute of Science and Technology
- Suzuki H, Takeuchi M, Sugiyama A, Alam A, Vu L, Sekiyama Y, et al. Alternative splicing produces structural and functional changes in CUGBP2. BMC Biochem. 2012;13:6 pubmed publisher..The present findings specifically show how alternative splicing events that result in three-dimensional structural changes in CUGBP2 can lead to changes in its biological activity. ..
- Suzuki H, Tsukahara T, Inoue K. Localization of c-mos mRNA around the animal pole in the zebrafish oocyte with Zor-1/Zorba. Biosci Trends. 2009;3:96-104 pubmed..Interestingly, we found c-mos mRNA is located in the animal cortex of zebrafish oocyte, where Zor-1 protein exists. Taken together, these results suggest that the animal cortex is the central core of oocyte maturation in zebrafish. ..
- Suzuki H, Kameyama T, Ohe K, Tsukahara T, Mayeda A. Nested introns in an intron: evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA. FEBS Lett. 2013;587:555-61 pubmed publisher..Nested splicing events, which bring the authentic 5' and 3' splice sites into close proximity, could be one of the splicing mechanisms for the extremely large introns. ..
- Alam S, Suzuki H, Tsukahara T. Alternative splicing regulation of APP exon 7 by RBFox proteins. Neurochem Int. 2014;78:7-17 pubmed publisher..Overall, RBFox proteins may shift APP from exon 7 containing isoforms, APP770 and APP751, toward the exon 7 lacking isoform, APP695, which is predominant in neural tissues. ..