Affiliation: Hokkaido University
- Kobashi G, Hata A, Ohta K, Yamada H, Kato E, Minakami H, et al. A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene. J Hum Genet. 2004;49:182-6 pubmed..The present results suggest that the C1166 allele of the AT1 gene may be concerned with the predisposition to essential hypertension independently of the T235 allele of the AGT gene. ..
- Kobashi G. Genetic and environmental factors associated with the development of hypertension in pregnancy. J Epidemiol. 2006;16:1-8 pubmed..Through further exploration of the risk factors associated with HP, we hope to provide useful suggestions about the development of new and effective preventive measures for a range of multifactorial diseases. ..
- Kobashi G, Washio M, Okamoto K, Sasaki S, Yokoyama T, Miyake Y, et al. High body mass index after age 20 and diabetes mellitus are independent risk factors for ossification of the posterior longitudinal ligament of the spine in Japanese subjects: a case-control study in multiple hospitals. Spine (Phila Pa 1976). 2004;29:1006-10 pubmed..A sex- and age-matched case-control study was carried out...
- Kobashi G, Kato E, Morikawa M, Shimada S, Ohta K, Fujimoto S, et al. MTHFR C677T Polymorphism and factor V Leiden mutation are not associated with recurrent spontaneous abortion of unexplained etiology in Japanese women. Semin Thromb Hemost. 2005;31:266-71 pubmed..0% and 16.7%, respectively. In addition, no Leiden mutation of FV was detected in the women with RSA or the controls. Neither T677 of the MTHFR nor the Leiden mutation of FV was associated with unexplained RSA in the Japanese population. ..