Genomes and Genes
Affiliation: Health Sciences University of Hokkaido
- Suzuki Y. Role of IGFBPs in the morphogenesis of lingual papillae. Anat Rec A Discov Mol Cell Evol Biol. 2005;286:841-7 pubmed..As previously suggested from a study on postnatal mice (Suzuki et al. J Comp Neurol 2005;482:74-84), IGFBP-4 acts in the epithelial invagination to form the trenches, grooves, or furrows of lingual papillae during development. ..
- Suzuki Y, Takeda M, Obara N. Expression of NeuroD in the mouse taste buds. Cell Tissue Res. 2002;307:423-8 pubmed..These results suggest that NeuroD is expressed in a mature cell type, type-II cells, but not in type-III cells. ..
- Suzuki Y, Mizoguchi I, Nishiyama H, Takeda M, Obara N. Expression of Hes6 and NeuroD in the olfactory epithelium, vomeronasal organ and non-sensory patches. Chem Senses. 2003;28:197-205 pubmed..At P3-P7, expression of NeuroD and Hes6 disappeared in the region corresponding to the presumptive non-sensory patches. The loss of these genes may stop the differentiation and may cause apoptosis of GBCs and ORNs. ..
- Suzuki Y, Tsuruga E, Yajima T, Takeda M. Expression of bHLH transcription factors NSCL1 and NSCL2 in the mouse olfactory system. Chem Senses. 2003;28:603-8 pubmed..Moreover, the temporal pattern of expression suggests that NSCL1 and NSCL2 may function during development rather than in the adult stage...
- Suzuki Y. Expression of Sox2 in mouse taste buds and its relation to innervation. Cell Tissue Res. 2008;332:393-401 pubmed publisher..Sox2-IR cells were found in the populations of basal cells and of immature and some mature taste bud cells. A large number of Sox2-IR cells were identified as type-I cells, with a few being type-II and type-III cells. ..
- Suzuki Y, Ikeda K, Kawakami K. Regulatory role of Six1 in the development of taste papillae. Cell Tissue Res. 2010;339:513-25 pubmed publisher..Thus, the modulation of signaling events in Six1 ( -/- ) leads to the earlier formation of the gustatory papillae, the abnormal distribution of fungiform papillae, and malformed trenches in circumvallate and foliate papillae. ..
- Suzuki Y, Ikeda K, Kawakami K. Expression of Six1 and Six4 in mouse taste buds. J Mol Histol. 2010;41:205-14 pubmed publisher..These results suggest that Six1 and Six4 genes are expressed in the taste bud cells, in newly formed or surviving type-II cells. ..
- Suzuki Y, Ikeda K, Kawakami K. Development of gustatory papillae in the absence of Six1 and Six4. J Anat. 2011;219:710-21 pubmed publisher..The foliate papillae elevated initially, and showed stunted trenches. Therefore, Six1 and Six4 function synergistically to form gustatory papillae during development of the tongue. ..