Genomes and Genes
Affiliation: Asahi Kasei Corporation
- BET, a novel neuronal transmembrane protein with multiple EGF-like motifsHirofumi Nishizumi
Department of Biophysics, Central Technology Laboratory, Asahi Kasei Corporation, 2 1 Samejima, Fuji, Shizuoka 416 8501, Japan
Neuroreport 13:909-15. 2002..BET is the first transmembrane protein containing only multiple EGF-like repeats specifically expressed in the brain...
- Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotencyTomoyuki Miyabayashi
Central R and D Laboratories, Asahi Kasei Corporation, Shizuoka 416 8501, Japan
Proc Natl Acad Sci U S A 104:5668-73. 2007..The increase in beta-catenin/CBP-mediated transcription at the expense of beta-catenin/p300-mediated transcription is critical for the maintenance of murine stem cell pluripotency...
- Indole derivatives sustain embryonic stem cell self-renewal in long-term cultureTomoyuki Miyabayashi
Central R and D Laboratories, Asahi Kasei Corporation, Fuji, Shizuoka 416 8501, Japan
Biosci Biotechnol Biochem 72:1242-8. 2008..These results indicate that our compounds provide a more efficient and safer large-scale culture system for pluripotent ESCs, and hence might contribute to the use of ESCs in therapeutic applications...