Maria Grazia Romanelli
Affiliation: University of Verona
Romanelli M, Tatò L, Lorenzi P, Morandi C. Nuclear localization domains in human thyroid transcription factor 2. Biochim Biophys Acta. 2003;1643:55-64 pubmed
..Taken together, our results provide the first documentation about nuclear targeting of a forkhead protein containing two identical NLS signal flanking the DNA-binding domain. ..
Diani E, Avesani F, Bergamo E, Cremonese G, Bertazzoni U, Romanelli M. HTLV-1 Tax protein recruitment into IKKÎµ and TBK1 kinase complexes enhances IFN-I expression. Virology. 2015;476:92-99 pubmed publisher
..We propose that Tax may be recruited into the TBK1/IKKÉ› complexes as a scaffolding-adaptor protein that enhances IFN-I gene expression. ..
Ferronato S, Gelati M, Scuro A, Olivato S, Malerba G, Romanelli M, et al
. HDAC9, TWIST1 and FERD3L gene expression in asymptomatic stable and unstable carotid plaques. Inflamm Res. 2016;65:261-3 pubmed publisher
..HDAC9 gene expression followed a similar trend (P = 0.11). These results highlighting the significant correlation between TWIST and HDAC9 gene expression suggest that both genes may contribute to plaque stability in a coordinated way. ..
Romanelli M, Lorenzi P, Avesani F, Morandi C. Functional characterization of the ribonucleoprotein, PTB-binding 1/Raver1 promoter region. Gene. 2007;405:79-87 pubmed
..Altogether, our results indicate that human Raver1 gene promoter region shares common features of ubiquitously expressed gene with the interacting splicing regulator PTB. ..
Romanelli M, Lorenzi P, Sangalli A, Diani E, Mottes M. Characterization and functional analysis of cis-acting elements of the human farnesyl diphosphate synthetase (FDPS) gene 5' flanking region. Genomics. 2009;93:227-34 pubmed publisher
Romanelli M, Lorenzi P, Diani E, Filippello A, Avesani F, Morandi C. Transcriptional regulation of the human Raver2 ribonucleoprotein gene. Gene. 2012;493:243-52 pubmed publisher
..Together, our results suggest that regulation of human Raver2 expression involves TATA-less transcriptional activity. ..
Romanelli M, Diani E, Lievens P. New insights into functional roles of the polypyrimidine tract-binding protein. Int J Mol Sci. 2013;14:22906-32 pubmed publisher
..Defining the multifunctional roles of PTB will contribute to the understanding of key regulatory events in gene expression. ..
Romanelli M, Lorenzi P, Morandi C. Identification and analysis of the human neural polypyrimidine tract binding protein (nPTB) gene promoter region. Gene. 2005;356:11-8 pubmed
..Alignment of human, murine and chimpanzee genomic sequences upstream the nPTB exon 1 has provided evidences for the evolutionary conservation of specific transcription factor binding sites. ..
Bergamo E, Diani E, Bertazzoni U, Romanelli M. A Luciferase Functional Quantitative Assay for Measuring NF-?B Promoter Transactivation Mediated by HTLV-1 and HTLV-2 Tax Proteins. Methods Mol Biol. 2017;1582:79-87 pubmed publisher
..This assay is particularly useful to investigate Tax influence on NF-?B activation mediated by viral or host factors. ..