Genomes and Genes
Affiliation: University of Pisa
- Coppede F, Ceravolo R, Migheli F, Fanucchi F, Frosini D, Siciliano G, et al. The hOGG1 Ser326Cys polymorphism is not associated with sporadic Parkinson's disease. Neurosci Lett. 2010;473:248-51 pubmed publisher..Moreover, the hOGG1 Ser326Cys polymorphism was not associated with disease age at onset (p=0.791). Overall, present results suggest that the hOGG1 Ser326Cys polymorphism is not associated with sporadic PD. ..
- Coppede F, Migliore L. DNA repair in premature aging disorders and neurodegeneration. Curr Aging Sci. 2010;3:3-19 pubmed..Here, we review the current knowledge on the role of DNA repair in premature aging and neurodegenerative diseases...
- Coppede F, Bosco P, Tannorella P, Romano C, Antonucci I, Stuppia L, et al. DNMT3B promoter polymorphisms and maternal risk of birth of a child with Down syndrome. Hum Reprod. 2013;28:545-50 pubmed publisher..If confirmed in subsequent studies, DNMT3B promoter polymorphisms might be additional markers to be taken into account when evaluating the contribution of one-carbon (folate) metabolism to the maternal risk of birth of a child with DS. ..
- Coppede F, Bosco P, Lorenzoni V, Migheli F, Barone C, Antonucci I, et al. The MTR 2756A>G polymorphism and maternal risk of birth of a child with Down syndrome: a case-control study and a meta-analysis. Mol Biol Rep. 2013;40:6913-25 pubmed publisher..No association of the studied polymorphism with circulating levels of hcy, folates, and vitamin B12 was observed. Present data do not support a role for MTR 2756A>G as independent maternal risk factor for a DS birth. ..