Affiliation: University of Messina
- Gugliandolo A, Gangemi C, CalabrÃ² C, Vecchio M, Di Mauro D, Renis M, et al. Assessment of glutathione peroxidase-1 polymorphisms, oxidative stress and DNA damage in sensitivity-related illnesses. Life Sci. 2016;145:27-33 pubmed publisher..However, these differences were not associated to GPx1 genetic background. GPx1 rs1800668 polymorphism does not play a major role in SRI-related oxidative stress development. ..
- Ferlazzo N, Currò M, Zinellu A, Caccamo D, Isola G, Ventura V, et al. Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer. Int J Mol Sci. 2017;18: pubmed publisher..The frequency of p16 and MGMT methylation was around 60% in patients with either the CT/AC or TT/AA genotype. Our results suggest that hypermethylation of cancer-related genes may be affected by MTHFR polymorphisms. ..
- Caccamo D, Gorgone G, Currò M, Parisi G, Di Iorio W, Menichetti C, et al. Effect of MTHFR polymorphisms on hyperhomocysteinemia in levodopa-treated Parkinsonian patients. Neuromolecular Med. 2007;9:249-54 pubmed..A better understanding of the role of homocysteine and MTHFR genotypes in PD is needed to reveal novel approaches for disease management. ..
- Russo T, Currò M, Barbera A, Caccamo D, Antonuccio P, Arena S, et al. Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. Int J Mol Sci. 2016;17: pubmed publisher..Increased expression of TG2 can be the result of chronic inflammation. TG2 overexpression can play a pivotal role in triggering and maintaining the inflammatory response in BXO patients. ..