Research Topics
| Linda SommeseSummaryAffiliation: Second University of Naples Country: Italy Publications
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Detail Information
Publications
Possible Muscle Repair in the Human Cardiovascular SystemLinda Sommese
Department of Internal and Specialty Medicine, U O C Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Università degli Studi della Campania Luigi Vanvitelli, Piazza Miraglia 2, 80138, Naples, Italy
Stem Cell Rev . 2017..This latter issue, involving genetic manipulations of adult cells, paves the way for developing possible therapeutic strategies in the field of cardiovascular muscle repair...- Syphilis detection: evaluation of serological screening and pilot reverse confirmatory assay algorithm in blood donorsLinda Sommese
U O C Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
Int J STD AIDS 27:644-9. 2016..A confirmatory strategy based on the use of two treponemal assays could meet the screening requirements for blood donors as well as in our centre. .. 
Severe Type 2 Diabetes Induces Reversible Modifications of Endothelial Progenitor Cells Which are Ameliorate by Glycemic ControlMaria Rosaria De Pascale
U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistics, Azienda Ospedaliera Universitaria, Second University of Naples
Int J Stem Cells 9:137-44. 2016..There is a growing evidence that hyperglycemia related to Diabetes Mellitus (DM) decreases EPC number and function so promoting vascular complications...- Lights and shadows of anti-HLA antibodies detected by solid-phase assayAntonietta Picascia
U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Piazza L Miraglia 2, 80138 Naples, Italy Electronic address
Immunol Lett 162:181-7. 2014..An open debate on the clinical relevance of anti-HLA antibodies detected by single-antigen beads highlights needing to further investigations. Here, we describe the novel applications and the improvements of the solid-phase assay use. .. - Evidence of Bacteroides fragilis protection from Bartonella henselae-induced damageLinda Sommese
Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Universitaria Policlinico, 1st School of Medicine, Second University of Naples, Naples, Italy
PLoS ONE 7:e49653. 2012..fragilis colonization was also able to restore the EPC decrease observed in mice infected with B. henselae (0.65 vs 0.06 media). Thus, our data establish that B. fragilis colonization is able to prevent B. henselae damages through PSA... - Effects of nitric oxide on cell proliferation: novel insightsClaudio Napoli
Department of General Pathology, Excellence Research Centre on Cardiovascular Diseases, U O C Immunohematology, Second University of Naples, Naples, Italy
J Am Coll Cardiol 62:89-95. 2013..This growing field may lead to broad and novel targeted therapies against cardiovascular diseases, especially concomitant type 2 diabetes, as well as novel bioimaging NO-based diagnostic tools... - Comparison of performance of two Treponema pallidum automated chemiluminescent immunoassays in blood donorsLinda Sommese
a U O C Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal and Specialty Medicine, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
Infect Dis (Lond) 48:483-7. 2016..01 for both). The overall agreement was 99.80% and the Cohen's kappa coefficients was 0.79. In conclusion, the recent Elecsys Syphilis assay could represent another reliable assay for blood donor screening. .. - Novel epigenetic-based therapies useful in cardiovascular medicineClaudio Napoli
Claudio Napoli, Vincenzo Grimaldi, Maria Rosaria De Pascale, Linda Sommese, Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria AOU, Second University of Naples, 80138 Naples, Italy
World J Cardiol 8:211-9. 2016.... - Screening tests for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus in blood donors: evaluation of two chemiluminescent immunoassay systemsLinda Sommese
From the 1 U O C Immunohaematology, Transfusion Medicine and Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples
Scand J Infect Dis 46:660-4. 2014..This study represents the first stringent comparison between Architect i2000SR and Cobas e411 in blood donors. We observed a good correlation and high agreement among HBV, HCV, and HIV with the 2 automated systems... - Current clinical applications of extracorporeal photochemotherapyMaria Capuano
U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
Ther Apher Dial 19:103-10. 2015..Since the study of such predictors is important, we also describe some biological markers that enable us to investigate the clinical management of the patients considered for the use of ECP. .. - Infections and cardiovascular disease: is Bartonella henselae contributing to this matter?Paola Salvatore
1 Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Naples, Italy 2 CEINGE Advanced Biotechnologies, Naples, Italy
J Med Microbiol 64:799-809. 2015.... - Seroprevalence of Bartonella henselae in patients awaiting heart transplant in Southern ItalyAntonietta Picascia
Department of Molecular Medicine and Medical Biotechnology, Federico II University Medical School, Naples, Italy U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples, Naples, Italy Electronic address
J Microbiol Immunol Infect . 2015..henselae in patients awaiting heart transplant compared to healthy individuals enrolled in the Regional Reference Laboratory of Transplant Immunology of Second University of Naples... - Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitusLinda Sommese
a U O C Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal and Specialty Medicine, Azienda Ospedaliera Universitaria AOU, Università degli Studi della Campania Luigi Vanvitelli, Italy
Epigenetics . 2017..Therefore, prevention or reversion of the epigenetic changes occurring during T2DM development may reduce the individual and societal burden of the disease... - Association between human leukocyte antigen class I and II alleles and hepatitis C virus infection in high-risk hemodialysis patients awaiting kidney transplantationVincenzo Grimaldi
U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy Electronic address
Hum Immunol 74:1629-32. 2013..Our results suggest that particular HLA molecules, as host genetic factors, may have a relationship with susceptibility or protection to HCV infection also in recipients awaiting kidney transplantation... - Massive-scale RNA-Seq analysis of non ribosomal transcriptome in human trisomy 21Valerio Costa
Institute of Genetics and Biophysics A Buzzati Traverso, CNR, Naples, Italy
PLoS ONE 6:e18493. 2011.... - Platelet derivatives in regenerative medicine: an updateMaria Rosaria De Pascale
UOC Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
Transfus Med Rev 29:52-61. 2015..Because the rationale of the therapy with platelet-derived compounds is still debated, a definitive insight can be acquired only when these large randomized trials will be completed. .. - Impact of epigenetic mechanisms on therapeutic approaches of hemoglobinopathiesDário Costa
U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Italy Electronic address
Blood Cells Mol Dis 55:95-100. 2015..The aim of this review was to report an update on the dynamic epigenetic modifications as targets for therapy in hemoglobinopathies. .. - Renal function impairment predicts mortality in patients with chronic heart failure treated with resynchronization therapyEdoardo Gronda
Fondazione Studio Diagnostica Nucleare, IRCCS, Naples, Italy Department of Internal Medicine and Specialist Units, U O C Immunohematology, and Excellence Research Center on Cardiovascular Disease, 1st School of Medicine, Second University of Naples, Naples, Italy
Cardiol J 22:459-66. 2015.... - Comparison between screening and confirmatory serological assays in blood donors in a region of South ItalyLinda Sommese
U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Universitaria Policlinico AOU, Second University of Naples, Italy
J Clin Lab Anal 28:198-203. 2014..It is important to evaluate the positive predictive value (PPV) of screening assays in order to modulate confirmatory algorithm and implement an adequate counseling... - Efforts in blood safety: Integrated approach for serological diagnosis of syphilisLinda Sommese
Department of Transfusion Medicine and Transplant Immunology, U O C Immunohematology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples, Italy
Asian J Transfus Sci 10:22-30. 2016.... - Platelet Gel in a Non-Regenerating Cryosurgery-Induced Skin Wound in an Old Patient: A Case ReportOrlando Pignalosa
Unitx00E0 Operativa Complessa, Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria, Second University of Naples, Naples, Italy
Med Princ Pract 25:388-90. 2016..To report on the clinical benefits of platelet gel application in a non-regenerating skin wound... - Impairment of circulating endothelial progenitors in Down syndromeValerio Costa
Institute of Genetics and Biophysics A, Buzzati Traverso, IGB CNR, Naples, Italy
BMC Med Genomics 3:40. 2010..The aim of our study was to elucidate some features of circulating endothelial progenitor cells in the context of this syndrome... - CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancyFilomena de Nigris
Division of Clinical Pathology, Department of General Pathology, School of Medicine, Second University of Naples, 80138 Naples, Italy
Proc Natl Acad Sci U S A 107:14484-9. 2010..Thus, YY1 may represent a crucial molecular target for antiangiogenic therapy during cancer progression... - Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertensionClaudio Napoli
Department of General Pathology and Excellence Research Center on Cardiovascular Diseases, and Microbiology Section, 1st School of Medicine, II University of Naples, Naples, Italy
Am Heart J 156:1154.e1-8. 2008..However, whether ACE inhibitors have any clinically significant antiatherogenic effects remains still debated...