Linda Sommese

Summary

Affiliation: Second University of Naples
Country: Italy

Publications

  1. doi Possible Muscle Repair in the Human Cardiovascular System
    Linda Sommese
    Department of Internal and Specialty Medicine, U O C Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Università degli Studi della Campania Luigi Vanvitelli, Piazza Miraglia 2, 80138, Naples, Italy
    Stem Cell Rev . 2017
  2. doi Syphilis detection: evaluation of serological screening and pilot reverse confirmatory assay algorithm in blood donors
    Linda Sommese
    U O C Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Int J STD AIDS 27:644-9. 2016
  3. pmc Severe Type 2 Diabetes Induces Reversible Modifications of Endothelial Progenitor Cells Which are Ameliorate by Glycemic Control
    Maria Rosaria De Pascale
    U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistics, Azienda Ospedaliera Universitaria, Second University of Naples
    Int J Stem Cells 9:137-44. 2016
  4. doi Lights and shadows of anti-HLA antibodies detected by solid-phase assay
    Antonietta Picascia
    U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Piazza L Miraglia 2, 80138 Naples, Italy Electronic address
    Immunol Lett 162:181-7. 2014
  5. pmc Evidence of Bacteroides fragilis protection from Bartonella henselae-induced damage
    Linda Sommese
    Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Universitaria Policlinico, 1st School of Medicine, Second University of Naples, Naples, Italy
    PLoS ONE 7:e49653. 2012
  6. doi Effects of nitric oxide on cell proliferation: novel insights
    Claudio Napoli
    Department of General Pathology, Excellence Research Centre on Cardiovascular Diseases, U O C Immunohematology, Second University of Naples, Naples, Italy
    J Am Coll Cardiol 62:89-95. 2013
  7. doi Comparison of performance of two Treponema pallidum automated chemiluminescent immunoassays in blood donors
    Linda Sommese
    a U O C Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal and Specialty Medicine, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Infect Dis (Lond) 48:483-7. 2016
  8. pmc Novel epigenetic-based therapies useful in cardiovascular medicine
    Claudio Napoli
    Claudio Napoli, Vincenzo Grimaldi, Maria Rosaria De Pascale, Linda Sommese, Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria AOU, Second University of Naples, 80138 Naples, Italy
    World J Cardiol 8:211-9. 2016
  9. doi Screening tests for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus in blood donors: evaluation of two chemiluminescent immunoassay systems
    Linda Sommese
    From the 1 U O C Immunohaematology, Transfusion Medicine and Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples
    Scand J Infect Dis 46:660-4. 2014
  10. doi Current clinical applications of extracorporeal photochemotherapy
    Maria Capuano
    U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Ther Apher Dial 19:103-10. 2015

Collaborators

  • Francesco Cacciatore
  • Valerio Costa
  • Monica Rienzo
  • Giuseppe Paolisso
  • Raffaele Calabro
  • Claudia Angelini
  • Antonio Giordano
  • Claudio Napoli
  • Margherita Mutarelli
  • Massimiliano Marco Corsi
  • Toshio Hayashi
  • Ettore Crimi
  • Stefania Crispi
  • Diana C Marquez-Garban
  • Antonietta Picascia
  • Maria Rosaria De Pascale
  • Concetta Schiano
  • Vincenzo Grimaldi
  • Amelia Casamassimi
  • Orlando Pignalosa
  • Maria Capuano
  • Paola Salvatore
  • Roberta Colicchio
  • Dário Costa
  • Edoardo Gronda
  • Chiara Sabia
  • Maria Lourdes Montesano
  • Filomena de Nigris
  • Giovanni F Nicoletti
  • Giuseppe Bruzzese
  • Francesco Cavalca
  • Angelo Itro
  • Nicola Ferrara
  • Gianpaolo Tartaro
  • Sergio Brongo
  • Dario Martusciello
  • Maria R De Pascale
  • Antonio Liguori
  • Michelangela Barbieri
  • Ernesto Mezza
  • Luca Genovese
  • Dino Franco Vitale
  • Alberto Zullo
  • Lisa Innocenti
  • Renato Bragato
  • Luigi Padeletti
  • Chiara Pagliuca
  • Ciro Maiello
  • Francesco Paolo Mancini
  • Gabiria Pastore
  • Francesco Labonia
  • Francesco Donatelli
  • Rossella Fabbricini
  • Delia Parente
  • Pasquale Abete
  • Caterina Pagliarulo
  • Giovanni Francesco Nicoletti
  • Annunziata Gaetana Cicatiello
  • Francesco Castaldo
  • Francesco Paolo D'Armiento
  • Stefano Genovese
  • Andrea Renda
  • Gustavo De Iorio
  • Carmela Fiorito
  • Paride De Rosa
  • Antonella Petrillo
  • Louis J Ignarro
  • Alfredo Siani
  • Antonio Barbieri
  • Mario Petrillo
  • Andrea Fiore
  • Franco Rengo
  • Claudio Arra
  • Mohammed Al-Omran
  • Hermes J Garban
  • Valeria Crudele
  • Francesca Pentimalli
  • Letizia Cito
  • Alfonso Giovane

Detail Information

Publications24

  1. doi Possible Muscle Repair in the Human Cardiovascular System
    Linda Sommese
    Department of Internal and Specialty Medicine, U O C Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Università degli Studi della Campania Luigi Vanvitelli, Piazza Miraglia 2, 80138, Naples, Italy
    Stem Cell Rev . 2017
    ..This latter issue, involving genetic manipulations of adult cells, paves the way for developing possible therapeutic strategies in the field of cardiovascular muscle repair...
  2. doi Syphilis detection: evaluation of serological screening and pilot reverse confirmatory assay algorithm in blood donors
    Linda Sommese
    U O C Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Int J STD AIDS 27:644-9. 2016
    ..A confirmatory strategy based on the use of two treponemal assays could meet the screening requirements for blood donors as well as in our centre. ..
  3. pmc Severe Type 2 Diabetes Induces Reversible Modifications of Endothelial Progenitor Cells Which are Ameliorate by Glycemic Control
    Maria Rosaria De Pascale
    U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistics, Azienda Ospedaliera Universitaria, Second University of Naples
    Int J Stem Cells 9:137-44. 2016
    ..There is a growing evidence that hyperglycemia related to Diabetes Mellitus (DM) decreases EPC number and function so promoting vascular complications...
  4. doi Lights and shadows of anti-HLA antibodies detected by solid-phase assay
    Antonietta Picascia
    U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Piazza L Miraglia 2, 80138 Naples, Italy Electronic address
    Immunol Lett 162:181-7. 2014
    ..An open debate on the clinical relevance of anti-HLA antibodies detected by single-antigen beads highlights needing to further investigations. Here, we describe the novel applications and the improvements of the solid-phase assay use. ..
  5. pmc Evidence of Bacteroides fragilis protection from Bartonella henselae-induced damage
    Linda Sommese
    Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Universitaria Policlinico, 1st School of Medicine, Second University of Naples, Naples, Italy
    PLoS ONE 7:e49653. 2012
    ..fragilis colonization was also able to restore the EPC decrease observed in mice infected with B. henselae (0.65 vs 0.06 media). Thus, our data establish that B. fragilis colonization is able to prevent B. henselae damages through PSA...
  6. doi Effects of nitric oxide on cell proliferation: novel insights
    Claudio Napoli
    Department of General Pathology, Excellence Research Centre on Cardiovascular Diseases, U O C Immunohematology, Second University of Naples, Naples, Italy
    J Am Coll Cardiol 62:89-95. 2013
    ..This growing field may lead to broad and novel targeted therapies against cardiovascular diseases, especially concomitant type 2 diabetes, as well as novel bioimaging NO-based diagnostic tools...
  7. doi Comparison of performance of two Treponema pallidum automated chemiluminescent immunoassays in blood donors
    Linda Sommese
    a U O C Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal and Specialty Medicine, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Infect Dis (Lond) 48:483-7. 2016
    ..01 for both). The overall agreement was 99.80% and the Cohen's kappa coefficients was 0.79. In conclusion, the recent Elecsys Syphilis assay could represent another reliable assay for blood donor screening. ..
  8. pmc Novel epigenetic-based therapies useful in cardiovascular medicine
    Claudio Napoli
    Claudio Napoli, Vincenzo Grimaldi, Maria Rosaria De Pascale, Linda Sommese, Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria AOU, Second University of Naples, 80138 Naples, Italy
    World J Cardiol 8:211-9. 2016
    ....
  9. doi Screening tests for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus in blood donors: evaluation of two chemiluminescent immunoassay systems
    Linda Sommese
    From the 1 U O C Immunohaematology, Transfusion Medicine and Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples
    Scand J Infect Dis 46:660-4. 2014
    ..This study represents the first stringent comparison between Architect i2000SR and Cobas e411 in blood donors. We observed a good correlation and high agreement among HBV, HCV, and HIV with the 2 automated systems...
  10. doi Current clinical applications of extracorporeal photochemotherapy
    Maria Capuano
    U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Ther Apher Dial 19:103-10. 2015
    ..Since the study of such predictors is important, we also describe some biological markers that enable us to investigate the clinical management of the patients considered for the use of ECP. ..
  11. doi Infections and cardiovascular disease: is Bartonella henselae contributing to this matter?
    Paola Salvatore
    1 Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Naples, Italy 2 CEINGE Advanced Biotechnologies, Naples, Italy
    J Med Microbiol 64:799-809. 2015
    ....
  12. doi Seroprevalence of Bartonella henselae in patients awaiting heart transplant in Southern Italy
    Antonietta Picascia
    Department of Molecular Medicine and Medical Biotechnology, Federico II University Medical School, Naples, Italy U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples, Naples, Italy Electronic address
    J Microbiol Immunol Infect . 2015
    ..henselae in patients awaiting heart transplant compared to healthy individuals enrolled in the Regional Reference Laboratory of Transplant Immunology of Second University of Naples...
  13. pmc Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus
    Linda Sommese
    a U O C Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal and Specialty Medicine, Azienda Ospedaliera Universitaria AOU, Università degli Studi della Campania Luigi Vanvitelli, Italy
    Epigenetics . 2017
    ..Therefore, prevention or reversion of the epigenetic changes occurring during T2DM development may reduce the individual and societal burden of the disease...
  14. doi Association between human leukocyte antigen class I and II alleles and hepatitis C virus infection in high-risk hemodialysis patients awaiting kidney transplantation
    Vincenzo Grimaldi
    U O C Division of Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy Electronic address
    Hum Immunol 74:1629-32. 2013
    ..Our results suggest that particular HLA molecules, as host genetic factors, may have a relationship with susceptibility or protection to HCV infection also in recipients awaiting kidney transplantation...
  15. pmc Massive-scale RNA-Seq analysis of non ribosomal transcriptome in human trisomy 21
    Valerio Costa
    Institute of Genetics and Biophysics A Buzzati Traverso, CNR, Naples, Italy
    PLoS ONE 6:e18493. 2011
    ....
  16. doi Platelet derivatives in regenerative medicine: an update
    Maria Rosaria De Pascale
    UOC Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Regional Reference Laboratory of Transplant Immunology LIT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Naples, Italy
    Transfus Med Rev 29:52-61. 2015
    ..Because the rationale of the therapy with platelet-derived compounds is still debated, a definitive insight can be acquired only when these large randomized trials will be completed. ..
  17. doi Impact of epigenetic mechanisms on therapeutic approaches of hemoglobinopathies
    Dário Costa
    U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Ospedaliera Universitaria AOU, Second University of Naples, Italy Electronic address
    Blood Cells Mol Dis 55:95-100. 2015
    ..The aim of this review was to report an update on the dynamic epigenetic modifications as targets for therapy in hemoglobinopathies. ..
  18. doi Renal function impairment predicts mortality in patients with chronic heart failure treated with resynchronization therapy
    Edoardo Gronda
    Fondazione Studio Diagnostica Nucleare, IRCCS, Naples, Italy Department of Internal Medicine and Specialist Units, U O C Immunohematology, and Excellence Research Center on Cardiovascular Disease, 1st School of Medicine, Second University of Naples, Naples, Italy
    Cardiol J 22:459-66. 2015
    ....
  19. doi Comparison between screening and confirmatory serological assays in blood donors in a region of South Italy
    Linda Sommese
    U O C Immunohematology, Transfusion Medicine and Transplant Immunology SIMT, Azienda Universitaria Policlinico AOU, Second University of Naples, Italy
    J Clin Lab Anal 28:198-203. 2014
    ..It is important to evaluate the positive predictive value (PPV) of screening assays in order to modulate confirmatory algorithm and implement an adequate counseling...
  20. pmc Efforts in blood safety: Integrated approach for serological diagnosis of syphilis
    Linda Sommese
    Department of Transfusion Medicine and Transplant Immunology, U O C Immunohematology, Regional Reference Laboratory of Transplant Immunology, Azienda Ospedaliera Universitaria, Second University of Naples, Italy
    Asian J Transfus Sci 10:22-30. 2016
    ....
  21. pmc Platelet Gel in a Non-Regenerating Cryosurgery-Induced Skin Wound in an Old Patient: A Case Report
    Orlando Pignalosa
    Unitx00E0 Operativa Complessa, Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria, Second University of Naples, Naples, Italy
    Med Princ Pract 25:388-90. 2016
    ..To report on the clinical benefits of platelet gel application in a non-regenerating skin wound...
  22. pmc Impairment of circulating endothelial progenitors in Down syndrome
    Valerio Costa
    Institute of Genetics and Biophysics A, Buzzati Traverso, IGB CNR, Naples, Italy
    BMC Med Genomics 3:40. 2010
    ..The aim of our study was to elucidate some features of circulating endothelial progenitor cells in the context of this syndrome...
  23. pmc CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy
    Filomena de Nigris
    Division of Clinical Pathology, Department of General Pathology, School of Medicine, Second University of Naples, 80138 Naples, Italy
    Proc Natl Acad Sci U S A 107:14484-9. 2010
    ..Thus, YY1 may represent a crucial molecular target for antiangiogenic therapy during cancer progression...
  24. doi Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension
    Claudio Napoli
    Department of General Pathology and Excellence Research Center on Cardiovascular Diseases, and Microbiology Section, 1st School of Medicine, II University of Naples, Naples, Italy
    Am Heart J 156:1154.e1-8. 2008
    ..However, whether ACE inhibitors have any clinically significant antiatherogenic effects remains still debated...