I Donatelli

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. pmc A sensitive one-step real-time PCR for detection of avian influenza viruses using a MGB probe and an internal positive control
    Livia Di Trani
    Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità V le Regina Elena 299, 00161 Rome, Italy
    BMC Infect Dis 6:87. 2006
  2. ncbi request reprint Influenza viruses: structure and interspecies transmission mechanisms
    I Donatelli
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    Vet Res Commun 27:115-22. 2003
  3. ncbi request reprint [WHO Influenza Global Agenda]
    Isabella Donatelli
    Laboratorio di Virologia, Istituto Superiore di Sanita, Roma
    Ann Ist Super Sanita 39:425-33. 2003
  4. ncbi request reprint Continued evolution of H1N1 and H3N2 influenza viruses in pigs in Italy
    L Campitelli
    Department of Virology, Istituto Superiore di Sanita, Rome, Italy
    Virology 232:310-8. 1997
  5. ncbi request reprint Characterization of H5N2 influenza viruses from Italian poultry
    I Donatelli
    , Rome, Italy
    J Gen Virol 82:623-30. 2001
  6. ncbi request reprint Amino acid changes in the attachment G glycoprotein of human respiratory syncytial viruses (subgroup A) isolated in Italy over several epidemics (1997-2006)
    S Montieri
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 79:1935-42. 2007
  7. ncbi request reprint Molecular surveillance of pandemic influenza A(H1N1) viruses circulating in Italy from May 2009 to February 2010: association between haemagglutinin mutations and clinical outcome
    S Puzelli
    Department of Infectious, Parasitic and Immune Mediated Diseases, National Institute of Health Istituto Superiore di Sanità ISS, Rome, Italy
    Euro Surveill 15:. 2010
  8. pmc Safety and immunogenicity of co-administered MF59-adjuvanted 2009 pandemic and plain 2009-10 seasonal influenza vaccines in rheumatoid arthritis patients on biologicals
    F Milanetti
    Department of Clinical and Molecular Medicine, S Andrea University Hospital, Sapienza University of Rome, Rome, Italy
    Clin Exp Immunol 177:287-94. 2014
  9. ncbi request reprint Investigation of an imported case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection in Florence, Italy, May to June 2013
    S Puzelli
    National Influenza Centre, Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore Sanita, Rome, Italy
    Euro Surveill 18:. 2013
  10. ncbi request reprint Serosurvey against H5 and H7 avian influenza viruses in Italian poultry workers
    L Di Trani
    Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
    Avian Dis 56:1068-71. 2012

Collaborators

Detail Information

Publications31

  1. pmc A sensitive one-step real-time PCR for detection of avian influenza viruses using a MGB probe and an internal positive control
    Livia Di Trani
    Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità V le Regina Elena 299, 00161 Rome, Italy
    BMC Infect Dis 6:87. 2006
    ..Therefore we developed a one-step reverse transcription real time PCR (RRT-PCR) with a Minor Groove Binder (MGB) probe for the detection of different subtypes of AIVs. This technique also includes an IPC...
  2. ncbi request reprint Influenza viruses: structure and interspecies transmission mechanisms
    I Donatelli
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    Vet Res Commun 27:115-22. 2003
  3. ncbi request reprint [WHO Influenza Global Agenda]
    Isabella Donatelli
    Laboratorio di Virologia, Istituto Superiore di Sanita, Roma
    Ann Ist Super Sanita 39:425-33. 2003
    ..The WHO Global Influenza Programme intends to maintain the current momentum of international strategy development and will continue to provide leadership in influenza prevention and control...
  4. ncbi request reprint Continued evolution of H1N1 and H3N2 influenza viruses in pigs in Italy
    L Campitelli
    Department of Virology, Istituto Superiore di Sanita, Rome, Italy
    Virology 232:310-8. 1997
    ..We strongly recommend that pigs be regularly monitored as a potential early warning system for detection of future pandemic strains...
  5. ncbi request reprint Characterization of H5N2 influenza viruses from Italian poultry
    I Donatelli
    , Rome, Italy
    J Gen Virol 82:623-30. 2001
    ..No virological and serological evidence of bird-to-human transmission of the Italian H5N2 influenza viruses was found...
  6. ncbi request reprint Amino acid changes in the attachment G glycoprotein of human respiratory syncytial viruses (subgroup A) isolated in Italy over several epidemics (1997-2006)
    S Montieri
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 79:1935-42. 2007
    ....
  7. ncbi request reprint Molecular surveillance of pandemic influenza A(H1N1) viruses circulating in Italy from May 2009 to February 2010: association between haemagglutinin mutations and clinical outcome
    S Puzelli
    Department of Infectious, Parasitic and Immune Mediated Diseases, National Institute of Health Istituto Superiore di Sanità ISS, Rome, Italy
    Euro Surveill 15:. 2010
    ..6%) and severe cases (38.4%). A cluster of D222E viruses among school children confirms reported human-to-human transmission of viruses mutated at amino acid position 222...
  8. pmc Safety and immunogenicity of co-administered MF59-adjuvanted 2009 pandemic and plain 2009-10 seasonal influenza vaccines in rheumatoid arthritis patients on biologicals
    F Milanetti
    Department of Clinical and Molecular Medicine, S Andrea University Hospital, Sapienza University of Rome, Rome, Italy
    Clin Exp Immunol 177:287-94. 2014
    ..The largely overlapping results between patients and HC, in terms of antibody response and cytokine-producing T cells, may represent further evidence for vaccine safety and immunogenicity in RA patients on biologicals. ..
  9. ncbi request reprint Investigation of an imported case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection in Florence, Italy, May to June 2013
    S Puzelli
    National Influenza Centre, Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore Sanita, Rome, Italy
    Euro Surveill 18:. 2013
    ..Two secondary cases were identified through contact tracing, among family members and colleagues who had not previously travelled abroad. Both secondary cases developed mild illness. All three patients recovered fully...
  10. ncbi request reprint Serosurvey against H5 and H7 avian influenza viruses in Italian poultry workers
    L Di Trani
    Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
    Avian Dis 56:1068-71. 2012
    ..In conclusion, the survey indicated that assessing seroprevalence can be an important tool in risk assessment and health,surveillance of poultry workers...
  11. ncbi request reprint Respiratory viruses and influenza-like illness: a survey in the area of Rome, winter 2004-2005
    G Rezza
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Euro Surveill 11:251-3. 2006
    ..Viral pathogens were identified in less than 50% of ILI cases occurred during a high activity influenza season. The detection of other than influenza viruses was sporadic, without evidence of large outbreaks due to specific agents...
  12. ncbi request reprint Influenza vaccine administration in patients with systemic lupus erythematosus and rheumatoid arthritis. Safety and immunogenicity
    F Del Porto
    Universita La Sapienza, II Facolta di Medicina e Chirurgia, Ospedale Sant Andrea, Cattedra ed U O C di Allergologia ed Immunologia Clinica, Rome, Italy
    Vaccine 24:3217-23. 2006
    ..To evaluate immunological safety and immunogenicity of influenza vaccine administration in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)...
  13. pmc Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A viruses
    Livia Di Trani
    Dept of Food and Animal Health, Istituto Superiore di Sanita, Rome, Italy
    Virol J 4:39. 2007
    ..Overall, the present study highlights the critical importance of a host cell factor such as intravesicular pH in determining the anti-influenza activity of chloroquine and other lysosomotropic agents...
  14. ncbi request reprint Evolutionary analysis of HA and NS1 genes of H5N1 influenza viruses in 2004-2005 epidemics
    Massimo Ciccozzi
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    Avian Dis 51:455-60. 2007
    ..Results showed that the number of HA positively selected sites decreased compared to 2004; no selection pressure for NS1 was found. These findings suggest a possible change in the adaptation of the H5N1 virus to birds...
  15. ncbi request reprint Characterization of human H1N1 influenza virus variants selected in vitro with zanamivir in the presence of sialic acid-containing molecules
    Simone Giannecchini
    Virology Unit, Department of Public Health, University of Florence, I 50134 Florence, Italy
    Virus Res 129:241-5. 2007
    ..Evidence that balanced neuraminidase and hemagglutinin activities mediated by mutations induced during selection could play a role in the decrease of virus replication susceptibility to zanamivir is reported...
  16. ncbi request reprint Type I IFN as a natural adjuvant for a protective immune response: lessons from the influenza vaccine model
    Enrico Proietti
    Department of Virology, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 169:375-83. 2002
    ....
  17. ncbi request reprint Molecular analysis of avian H7 influenza viruses circulating in Eurasia in 1999-2005: detection of multiple reassortant virus genotypes
    Laura Campitelli
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Gen Virol 89:48-59. 2008
    ..In turn this might help avian influenza viruses colonize a wider range of hosts, including domestic poultry...
  18. ncbi request reprint H3N2 influenza viruses from domestic chickens in Italy: an increasing role for chickens in the ecology of influenza?
    Laura Campitelli
    Department of Virology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Gen Virol 83:413-20. 2002
    ....
  19. ncbi request reprint Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus
    Laura Bracci
    Department of Cellular Biology and Neurosciences, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
    Vaccine 24:S2-56-7. 2006
    ..These findings shed new light on the involvement of type I IFN in the early phases of the immune response and open new and practical perspectives in vaccine research...
  20. ncbi request reprint Molecular characterization of influenza B viruses circulating in northern Italy during the 2001-2002 epidemic season
    Filippo Ansaldi
    Department of Public Medicine Sciences, U C O Hygiene and Preventive Medicine, University of Trieste and IRCCS Burlo Garofolo, Trieste, Italy
    J Med Virol 70:463-9. 2003
    ....
  21. ncbi request reprint Interspecies transmission of an H7N3 influenza virus from wild birds to intensively reared domestic poultry in Italy
    Laura Campitelli
    Department of Virology, Istituto Superiore Sanita, Rome, Italy
    Virology 323:24-36. 2004
    ....
  22. ncbi request reprint Changes in the hemagglutinins and neuraminidases of human influenza B viruses isolated in Italy during the 2001-02, 2002-03, and 2003-04 seasons
    Simona Puzelli
    Laboratory of Virology, National Influenza Centre, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 74:629-40. 2004
    ..The frequency of reassortment between HA and NA of distinct lineages and sublineages highlights again the importance of detailed molecular analyses of both surface glycoproteins in understanding the evolution of influenza B viruses...
  23. ncbi request reprint Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level
    Laura Bracci
    Department of Cell Biology and Neurosciences, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Vaccine 23:2994-3004. 2005
    ..Further experiments showed that IFNalphabeta increased the percentage of antigen-associated phagocytes in the nasal mucus layer, thus suggesting a new possible mechanism of action for type I IFN as an adjuvant...
  24. pmc New A/H3N2 influenza variant: a small genetic evolution but a heavy burden on the Italian population during the 2004-2005 season
    Filippo Ansaldi
    CIRI IV, Department of Health Sciences, University of Genoa, Genoa, Italy
    J Clin Microbiol 43:3027-9. 2005
  25. ncbi request reprint Serological analysis of serum samples from humans exposed to avian H7 influenza viruses in Italy between 1999 and 2003
    Simona Puzelli
    Department of Infectious, Parasitic and Immuno Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Infect Dis 192:1318-22. 2005
    ....
  26. ncbi request reprint Comparison of in vitro replication features of H7N3 influenza viruses from wild ducks and turkeys: potential implications for interspecies transmission
    Simone Giannecchini
    Virology Unit, Department of Public Health, University of Florence, Firenze, Italy
    J Gen Virol 87:171-5. 2006
    ....
  27. ncbi request reprint New insights into the antiviral effects of chloroquine
    Andrea Savarino
    Lancet Infect Dis 6:67-9. 2006
  28. ncbi request reprint Influenza virological surveillance in children: the use of the QuickVue rapid diagnostic test
    Fabrizio Pregliasco
    Institute of Virology, University of Milan, Milan, Italy
    J Med Virol 73:269-73. 2004
    ..Nevertheless, the QV test may be a valuable diagnostic tool if used in laboratory, as a rapid screening test...
  29. ncbi request reprint H5N1 influenza virus evolution: a comparison of different epidemics in birds and humans (1997-2004)
    Laura Campitelli
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Gen Virol 87:955-60. 2006
    ..Positive-selection analysis performed on single-codon sites might be helpful in clarifying the driving force of avian and human influenza virus evolution and in selecting specific targets for vaccines and antiviral drugs...
  30. ncbi request reprint Influenza virus circulation in wild aquatic birds in Italy during H5N2 and H7N1 poultry epidemic periods (1998 to 2000)
    Maria Alessandra De Marco
    Istituto Nazionale per la Fauna Selvatica A Ghigi, Ozzano Emilia BO, Italy
    Avian Pathol 34:480-5. 2005
    ..However, the H5 seroconversion observed in one mallard duck at the beginning of 1998 indicates that H5 virus circulation also occurred in the study area...
  31. ncbi request reprint Prevalence of antibodies against A and B influenza viruses in South-Western Papua New Guinea
    Simona Puzelli
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 78:820-4. 2006
    ..The data obtained confirm the co-circulation of these antigenic variants, reported having circulated in the Southern Hemisphere. Variations in seroprevalence of influenza A and B virus infection were found within the study area...