Affiliation: Nicholas Piramal India Limited
- Semisynthetic modifications of hemiaminal function at ornithine unit of mulundocandin, towards chemical stability and antifungal activityBansi Lal
Department of Medicinal Chemistry, Quest Institute of LifeSciences, Nicholas Piramal India Limited, Mulund w Mumbai 4000 80, India
Bioorg Med Chem 11:5189-98. 2003..Compound 9 has shown improved antifungal activity in comparison to mulundocandin by oral application in Swiss mice...
- Approaches towards the stabilization of hemiaminal function at ornithine unit of mulundocandinBansi Lal
Quest Institute of LifeScience, Nicholas Piramal India Limited, and Hoechst Research Center, Mulund, Mumbai 400080, Maharashtra, India
Bioorg Med Chem Lett 14:1123-8. 2004..Synthesized mulundocandin analogues were evaluated for their chemical stability and antifungal activity against C. albicans and A. fumigatus...
- Mannich reaction: an approach for the synthesis of water soluble mulundocandin analoguesBansi Lal
Quest Institute of LifeSciences, Nicholas Piramal India Limited, Mulund W, Mumbai 4000 80, India
Bioorg Med Chem 12:1751-68. 2004..Compound 20, showed significant improvement in activity over mulundocandin (1) and activity compares well with that of fluconazole...
- In vitro antitumor properties of a novel cyclin-dependent kinase inhibitor, P276-00Kalpana S Joshi
Department of Pharmacology, Nicholas Piramal Research Center, Nicholas Piramal India Limited, 1 Nirlon Complex, Goregaon E, Mumbai 400 063, India
Mol Cancer Ther 6:918-25. 2007..These data suggest that P276-00 has the potential to be developed as an anti-Cdk chemotherapeutic agent...