Arijit Biswas

Summary

Affiliation: Institute of Experimental Hematology and Transfusion Medicine
Location: Bonn, Germany
URL: http://www.ukb.uni-bonn.de/quick2web/internet/internet.nsf/04fa7deb65dc84f9c1256a6200552c10/787f24ed3fdedf48c12577f40046fa2c?OpenDocument
Summary:
Research on Factor XIII deficiency and structure functional relationships of Factor XIII
Publications:
1: Ivaskevicius V, Biswas A, Bevans C, Schroeder V, Kohler HP, Rott H, Halimeh S,
Petrides PE, Lenk H, Krause M, Miterski B, Harbrecht U, Oldenburg J.
Identification of eight novel coagulation factor XIII subunit A mutations:
implied consequences for structure and function. Haematologica. 2010
Jun;95(6):956-62. Epub 2010 Feb 23. PubMed PMID: ; PubMed Central PMCID:
PMC2878794.


2: Ivaskevicius V, Biswas A, Loreth R, Schroeder V, Ohlenforst S, Rott H, Krause
M, Kohler HP, Scharrer I, Oldenburg J. Mutations affecting disulphide bonds
contribute to a fairly common prevalence of F13B gene defects: results of a
genetic study in 14 families with factor XIII B deficiency. Haemophilia. 2010 Jul
1;16(4):675-82. Epub 2010 Mar 10. PubMed PMID: .


3: Biswas A, Ivaskevicius V, Seitz R, Thomas A, Oldenburg J. An update of the
mutation profile of Factor 13 A and B genes. Blood Rev. 2011 Sep;25(5):193-204.
Epub 2011 Jun 2. PubMed PMID: .

Publications

  1. pmc Identification of eight novel coagulation factor XIII subunit A mutations: implied consequences for structure and function
    Vytautas Ivaskevicius
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany
    Haematologica 95:956-62. 2010
  2. doi Mutations affecting disulphide bonds contribute to a fairly common prevalence of F13B gene defects: results of a genetic study in 14 families with factor XIII B deficiency
    V Ivaskevicius
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
    Haemophilia 16:675-82. 2010
  3. doi An update of the mutation profile of Factor 13 A and B genes
    Arijit Biswas
    Institute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, Germany
    Blood Rev 25:193-204. 2011
  4. doi Inter-locus as well as intra-locus heterogeneity in LINE-1 promoter methylation in common human cancers suggests selective demethylation pressure at specific CpGs.
    Nicole N sgen
    Institute of Experimental Hematology and Transfusion Medicine, University of Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Clin Epigenetics 7:17. 2015
  5. doi Eight novel F13A1 gene missense mutations in patients with mild FXIII deficiency: in silico analysis suggests changes in FXIII-A subunit structure/function
    Arijit Biswas
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Sigmund Freud Str 25, 53127, Bonn, Germany
    Ann Hematol 93:1665-76. 2014
  6. doi Coagulation factor XIII deficiency. Diagnosis, prevalence and management of inherited and acquired forms
    A Biswas
    Arijit Biswas Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Sigmund Freud Str 25 53127 Bonn, Germany, Tel 49 0 228 28 71 94 28, Fax 49 0 228 28 71 43 20, E mail
    Hamostaseologie 34:160-6. 2014

Collaborators

Detail Information

Publications6

  1. pmc Identification of eight novel coagulation factor XIII subunit A mutations: implied consequences for structure and function
    Vytautas Ivaskevicius
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany
    Haematologica 95:956-62. 2010
    ..In most cases, the disease is caused by F13A gene mutations. Causative mutations associated with the F13B gene are rarer...
  2. doi Mutations affecting disulphide bonds contribute to a fairly common prevalence of F13B gene defects: results of a genetic study in 14 families with factor XIII B deficiency
    V Ivaskevicius
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
    Haemophilia 16:675-82. 2010
    ..The present study reports on a fairly common prevalence of F13B gene defects in the German population. The regions in and around the cysteine disulphide bonds in the FXIII-B protein may be regions prone to frequent mutations...
  3. doi An update of the mutation profile of Factor 13 A and B genes
    Arijit Biswas
    Institute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, Germany
    Blood Rev 25:193-204. 2011
    ..The source of our mutational data is our website dedicated to Factor XIII deficiencies (www.F13-database.de) as well as literature search done on the Pubmed (www.ncbi.nlm.nih.gov/pubmed)...
  4. doi Inter-locus as well as intra-locus heterogeneity in LINE-1 promoter methylation in common human cancers suggests selective demethylation pressure at specific CpGs.
    Nicole N sgen
    Institute of Experimental Hematology and Transfusion Medicine, University of Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Clin Epigenetics 7:17. 2015
    ..With a broader selection of loci, locus-specific LINE-1 methylation could become a tool for tumor detection...
  5. doi Eight novel F13A1 gene missense mutations in patients with mild FXIII deficiency: in silico analysis suggests changes in FXIII-A subunit structure/function
    Arijit Biswas
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Sigmund Freud Str 25, 53127, Bonn, Germany
    Ann Hematol 93:1665-76. 2014
    ..In vitro expression and subsequent biochemical studies in the future will be able to confirm the pathophysiological mechanisms proposed for the mutations in this article. ..
  6. doi Coagulation factor XIII deficiency. Diagnosis, prevalence and management of inherited and acquired forms
    A Biswas
    Arijit Biswas Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Sigmund Freud Str 25 53127 Bonn, Germany, Tel 49 0 228 28 71 94 28, Fax 49 0 228 28 71 43 20, E mail
    Hamostaseologie 34:160-6. 2014
    ..Here, we update the knowledge about the pathophysiology of factor XIII deficiency and its therapeutic options. ..