C Grothe

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. request reprint
    Grothe C, Claus P, Haastert K, Lutwak E, Ron D. Expression and regulation of Sef, a novel signaling inhibitor of receptor tyrosine kinases-mediated signaling in the nervous system. Acta Histochem. 2008;110:155-62 pubmed
    ..These results suggest an involvement of Sef during the nerve regeneration process, possibly by fine-tuning the effects of FGF signaling. ..
  2. Rumpel R, Alam M, Schwarz L, Ratzka A, Jin X, Krauss J, et al. Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. Neuroscience. 2017;360:197-209 pubmed publisher
    ..Analysis of oscillatory activity revealed enhanced beta activity in both regions, which was reduced after grafting. In summary these data indicate restoration of BG motor loop toward normal activity by DA graft integration. ..
  3. request reprint
    Grothe C, Timmer M, Scholz T, Winkler C, Nikkhah G, Claus P, et al. Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons. Neurobiol Dis. 2004;17:163-70 pubmed
    ..Thus, our results suggest that FGF-20 promotes the differentiation of Nurr1-NSCs into TH-positive neurons and that additional factors are required for the efficient differentiation of DA neurons in the adult brain. ..

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Detail Information

Publications3

  1. request reprint
    Grothe C, Claus P, Haastert K, Lutwak E, Ron D. Expression and regulation of Sef, a novel signaling inhibitor of receptor tyrosine kinases-mediated signaling in the nervous system. Acta Histochem. 2008;110:155-62 pubmed
    ..These results suggest an involvement of Sef during the nerve regeneration process, possibly by fine-tuning the effects of FGF signaling. ..
  2. Rumpel R, Alam M, Schwarz L, Ratzka A, Jin X, Krauss J, et al. Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. Neuroscience. 2017;360:197-209 pubmed publisher
    ..Analysis of oscillatory activity revealed enhanced beta activity in both regions, which was reduced after grafting. In summary these data indicate restoration of BG motor loop toward normal activity by DA graft integration. ..
  3. request reprint
    Grothe C, Timmer M, Scholz T, Winkler C, Nikkhah G, Claus P, et al. Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons. Neurobiol Dis. 2004;17:163-70 pubmed
    ..Thus, our results suggest that FGF-20 promotes the differentiation of Nurr1-NSCs into TH-positive neurons and that additional factors are required for the efficient differentiation of DA neurons in the adult brain. ..