Affiliation: University of Helsinki
- Kaukinen P, Sillanpää M, Nousiainen L, Melen K, Julkunen I. Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKK? and TBK1 functions. J Med Virol. 2013;85:71-82 pubmed publisher..The present study identified HCV NS2 as a potent interferon antagonist, and describes an explanation of how NS2 downregulates the major signaling pathways involved in the development of host innate antiviral responses. ..