Cozzolino M, Brancaccio D, Gallieni M, Galassi A, Slatopolsky E, Dusso A. Pathogenesis of parathyroid hyperplasia in renal failure. J Nephrol. 2005;18:5-8 pubmed
..In this review, we analyze the current understanding concerning the new insights into the molecular mechanisms of parathyroid hyperplasia and PTH secretion in renal failure regulated by calcium, phosphate and vitamin D...
Cozzolino M, Galassi A, Biondi M, Turri O, Papagni S, Mongelli N, et al
. Serum fetuin-A levels link inflammation and cardiovascular calcification in hemodialysis patients. Am J Nephrol. 2006;26:423-9 pubmed
..Chronic inflammation in HD patients leads to lower serum fetuin-A levels. The present study confirms the independent and significant association between reduced serum fetuin-A levels and multi-site CVC in HD. ..
Cozzolino M, Brancaccio D. Hyperphosphatemia in dialysis patients: the therapeutic role of lanthanum carbonate. Int J Artif Organs. 2007;30:293-300 pubmed
..This review paper suggests that new calcium- and aluminum-free phosphate binders, such as lanthanum carbonate, can be used to treat hyperphosphatemia and secondary hyperparathyroidism in ESRD patients...
Cozzolino M, Gallieni M, Brancaccio D. The mechanisms of hyperphosphatemia-induced vascular calcification. Int J Artif Organs. 2008;31:1002-3 pubmed
..Therefore, control of serum phosphate in CKD patients becomes crucial in preventing increases in calcium x phosphate product, secondary hyperparathyroidism, and ultimately vascular calcification...
Cozzolino M, Biondi M, Galassi A, Turri O, Brancaccio D, Gallieni M. Matrix metalloproteinase-1 and matrix metalloproteinase-3 gene promoter polymorphisms are associated with mortality in haemodialysis patients. Nephrol Dial Transplant. 2009;24:2207-12 pubmed publisher
..These data may have important implications for better understanding the pathogenesis of the increased mortality in HD patients. ..
Cozzolino M, Pasho S, Fallabrino G, Olivi L, Gallieni M, Brancaccio D. Pathogenesis of secondary hyperparathyroidism. Int J Artif Organs. 2009;32:75-80 pubmed
..In contrast, the discovery of a parathyroid phosphate sensor or receptor has yet to be made...