Research Topics

Philip R Cohen



  1. Cohen P, Anderson C. Topical Selenium Sulfide for the Treatment of Hyperkeratosis. Dermatol Ther (Heidelb). 2018;: pubmed publisher
    ..In conclusion, we recommend that topical selenium sulfide be added to the therapeutic armamentarium for congenital or acquired hyperkeratosis-particularly for those patients with involvement of their palms and soles. ..
  2. Werbel T, Cohen P. Topical Application of 5-Fluorouracil Associated with Distant Seborrheic Dermatitis-like Eruption: Case Report and Review of Seborrheic Dermatitis Cutaneous Reactions after Systemic or Topical Treatment with 5-Fluorouracil. Dermatol Ther (Heidelb). 2018;8:495-501 pubmed publisher
    ..The etiologic association between the drug and adverse effect was confirmed with multiple cycles of application and discontinuation of the offending agent. ..
  3. Cohen P. Sorafenib-associated facial acneiform eruption. Dermatol Ther (Heidelb). 2015;5:77-86 pubmed publisher
    ..Topical acne-directed therapy was only partially effective in clearing the lesions; lowering the dose or discontinuation of sorafenib resulted in progressive improvement or resolution of the facial acneiform eruption. ..
  4. Cohen P, Kurzrock R. The checklist: BEST medical center employment requirements 2015. Clin Dermatol. 2015;33:493-7 pubmed publisher
    ..Lystic must prepay for all the paperwork/tests. While Dr. Ida Lystic and "the BEST Medical Center" are creations of the authors' imagination, most of the items on her checklists are real. ..
  5. Beutler B, Cohen P, Lee R. Prurigo Pigmentosa: Literature Review. Am J Clin Dermatol. 2015;16:533-43 pubmed publisher
    ..We describe the key features of prurigo pigmentosa, including the epidemiology, clinical and histologic presentation, differential diagnosis, postulated pathogenesis, and treatment options for this condition. ..
  6. Cohen P. Topical application of 5-fluorouracil 5 percent cream associated with severe neutropenia: discussion of a case and review of systemic reactions after topical treatment with 5-fluorouracil. Dermatol Online J. 2018;24: pubmed
    ..Also, the incidence of potentially severe 5-fluorouracil-induced toxicity associated with topical application of the drug may be greater than documented. ..
  7. Cohen P. Surgery at the BEST Medical Center-Clyde's Adventures in BEST Land: Down the Rabbit Hole. Clin Dermatol. 2018;36:576-580 pubmed publisher
    ..Fortunately, however, Clyde's insurance coverage is excellent, and all of his bills have been paid. ..
  8. Cohen P. Perforating osteoma cutis: case report and literature review of patients with a solitary perforating osteoma cutis lesion. Dermatol Online J. 2018;24: pubmed
    ..The perforating osteoma cutis lesion was successfully treated with either excision or shave biopsy without recurrence at either 10 or 12-months follow-up. ..
  9. Beutler B, Cohen P. Sarcoidosis in Melanoma Patients: Case Report and Literature Review. Cancers (Basel). 2015;7:1005-21 pubmed publisher
    ..In antineoplastic therapy naive melanoma patients, a common etiologic factor-such as exposure to ultraviolet light-may play a role in their developing melanoma and sarcoidosis. ..

More Information


  1. Cohen P, Kurzrock R. Merkel Cell Carcinoma with a Suppressor of Fused (SUFU) Mutation: Case Report and Potential Therapeutic Implications. Dermatol Ther (Heidelb). 2015;5:129-43 pubmed publisher
    ..We report a patient with a mutation in SUFU, a potentially actionable component of the Hh signaling pathway. ..
  2. Cohen P. Basal Cell Carcinoma of the Buttock. Skinmed. 2018;16:105-110 pubmed
    ..The cancer was typically associated with a nonaggressive histologic subtype. Recurrence or metastasis was not observed after treatment of the primary tumor. ..
  3. Natsis N, Cohen P. Coagulase-Negative Staphylococcus Skin and Soft Tissue Infections. Am J Clin Dermatol. 2018;: pubmed publisher
    ..They are usually susceptible to antibiotics used to treat methicillin-sensitive Staphylococcus aureus. ..
  4. Cohen B, Cohen E, Cohen P. Basal Cell Carcinoma: A Patient and Physician's Experience. Dermatol Ther (Heidelb). 2018;8:329-337 pubmed publisher
    ..The third coauthor, who is the patient's son and not only a dermatologist, but also a dermatopathologist and a Mohs surgeon (and also shares her last name), summarizes the presentation and treatment of the basal cell carcinoma. ..
  5. Vazirnia A, Cohen P. Poland's syndrome: a concise review of the clinical features highlighting associated dermatologic manifestations. Am J Clin Dermatol. 2015;16:295-301 pubmed publisher
    ..We summarize the key features of Poland's syndrome, including the epidemiology, clinical presentation, pathogenesis, and management, and highlight the dermatologic associations reported in the literature. ..
  6. Rappazzo K, Cohen P. Pigmented hidrocystoma of nasal epithelium (PHONE): report of a man with a pigmented hidrocystoma of his nose and literature review. Dermatol Online J. 2016;22: pubmed
    ..A biopsy readily establishes the diagnosis. We respectfully suggest that a hidrocystoma located on the nose that is pigmented be referred to as a PHONE: pigmented hidrocystoma of the nasal epithelium. ..
  7. Schepp E, Cohen P. Zosteriform Staphylococcus aureus Cutaneous Infection: Report of Two Patients With Dermatomal Bacterial Infection. Skinmed. 2015;13:275-81 pubmed
  8. Loh T, Cohen P. Darwin's Tubercle: Review of a Unique Congenital Anomaly. Dermatol Ther (Heidelb). 2016;6:143-9 pubmed publisher
    ..Darwin's tubercle is a benign and unique helical feature. It contributes to the individuality of human ears and may have applications toward personal identification in the future. ..
  9. Stiff K, Cohen P. Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review. Dermatol Ther (Heidelb). 2017;7:65-79 pubmed publisher
    ..Vegas xanthomas have been reported in association with a variety of diseases, as well as in healthy individuals. Biopsy is required for diagnosis, and complete surgical excision is typically curative. ..
  10. Cohen P. Bullous impetigo and pregnancy: Case report and review of blistering conditions in pregnancy. Dermatol Online J. 2016;22: pubmed
    ..aureus.  All of the lesions resolved after treatment with clindamycin.  Bullous impetigo should be considered in the differential diagnosis of common skin diseases presenting as blistersin pregnant women. ..
  11. Greywal T, Cohen P. Pitted keratolysis: successful management with mupirocin 2% ointment monotherapy. Dermatol Online J. 2015;21: pubmed
    ..Our patient confirms previous reports of pitted keratolysis resolving with mupirocin 2% ointment treatment. Monotherapy with mupirocin 2% ointment should be considered as a primary treatment alternative for pitted keratolysis. ..
  12. Cohen P. Trastuzumab-Associated Flagellate Erythema: Report in a Woman with Metastatic Breast Cancer and Review of Antineoplastic Therapy-Induced Flagellate Dermatoses. Dermatol Ther (Heidelb). 2015;5:253-264 pubmed
    ..However, flagellate erythema should be added to the potential side effects of trastuzumab. In addition, trastuzumab should be added to the list of antineoplastic agents that may be associated with flagellate erythema. ..
  13. Cohen P. Injection Site Lichenoid Dermatitis Following Pneumococcal Vaccination: Report and Review of Cutaneous Conditions Occurring at Vaccination Sites. Dermatol Ther (Heidelb). 2016;6:287-98 pubmed publisher
    ..A cutaneous immunocompromised district that is created by vaccine-induced local immunologic changes is hypothesized to be the pathogenesis of vaccination site reactions. ..
  14. Udkoff J, Cohen P. Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn's Disease: Dramatic Improvement after Drug Discontinuation and Treatment with Adjuvant Systemic and Topical Therapies. Dermatol Ther (Heidelb). 2016;6:689-695 pubmed
  15. Cohen P, Kurzrock R. My personal experiences at the BEST Medical Center: A day in the clinic-the morning. Clin Dermatol. 2016;34:422-5 pubmed publisher
    ..Although Dr. Ida Lystic and the gastroenterology clinic at "the BEST Medical Center" are creations of the authors' imagination, the majority of the anecdotes are based on actual events. ..
  16. Cohen P. Segmental neurofibromatosis and cancer: report of triple malignancy in a woman with mosaic Neurofibromatosis 1 and review of neoplasms in segmental neurofibromatosis. Dermatol Online J. 2016;22: pubmed
    ..ConclusionsSimilar to patients with von Recklinghausen neurofibromatosis 1, individuals with segmental neurofibromatosis also have a genodermatosis-associated increased risk of developing cancer. ..
  17. Udkoff J, Cohen P. Amyopathic Dermatomyositis: A Concise Review of Clinical Manifestations and Associated Malignancies. Am J Clin Dermatol. 2016;17:509-518 pubmed
    ..However, in contrast to lung cancer, which is the most frequent malignancy associated with classic dermatomyositis, breast cancer was the most common type of malignancy reported in patients with amyopathic dermatomyosotis. ..
  18. Heldt Manica L, Cohen P. Ibrutinib-Associated Nail Plate Abnormalities: Case Reports and Review. Drug Saf Case Rep. 2017;4:15 pubmed publisher
    ..In conclusion, ibrutinib is used to treat chronic lymphocytic leukemia. It is usually well-tolerated. Many patients receiving ibrutinib will develop nail plate abnormalities. This adverse event is not a drug-limiting toxicity. ..
  19. Cohen P. Fellowship candidate selection at the BEST Medical Center: A novel process. Clin Dermatol. 2017;35:485-488 pubmed publisher
  20. Cohen P, Kato S, Goodman A, Ikeda S, Kurzrock R. Appearance of New Cutaneous Superficial Basal Cell Carcinomas during Successful Nivolumab Treatment of Refractory Metastatic Disease: Implications for Immunotherapy in Early Versus Late Disease. Int J Mol Sci. 2017;18: pubmed publisher
  21. Schneider J, Cohen P. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures. Adv Ther. 2017;34:1235-1244 pubmed publisher
    ..Therefore, until further data are available, decisions regarding such treatments should be made on a case-by-case basis. ..
  22. Chang C, Beutler B, Cohen P. Polydactylous Transverse Erythronychia: Report of a Patient with Multiple Horizontal Red Bands Affecting the Fingernails. Dermatol Ther (Heidelb). 2017;7:255-262 pubmed publisher
    ..In our patient, both transverse and longitudinal red bands were present simultaneously. Therefore, it is possible that horizontal erythronychia is an early clinical manifestation of longitudinal erythronychia. ..
  23. Heldt Manica L, Cohen P. Staphylococcus lugdunensis Infections of the Skin and Soft Tissue: A Case Series and Review. Dermatol Ther (Heidelb). 2017;7:555-562 pubmed publisher
    ..lugdunensis can result in significant skin and soft tissue infections, perhaps more frequently in older individuals. Its antibiotic sensitivities appear to be similar to those of methicillin-susceptible Staphylococcus aureus. ..
  24. Beutler B, Cohen P. Angiokeratoma of the Glans Penis. Skinmed. 2017;15:343-347 pubmed
    ..Biopsy would exclude a melanocytic lesion, particularly melanoma. Laser surgery is an option for patients presenting with multiple lesions or lesions that coalesce to form a plaque...
  25. Chen S, Cohen P. Parrot Beak Nails Revisited: Case Series and Comprehensive Review. Dermatol Ther (Heidelb). 2018;8:147-155 pubmed publisher
    ..Therefore, it is important for clinicians to look for these nail lesions on cutaneous examination and recommend frequent nail trimmings to individuals with parrot beak nails. ..
  26. Tong Y, Schneider J, Coda A, Hata T, Cohen P. Birt-Hogg-Dubé Syndrome: A Review of Dermatological Manifestations and Other Symptoms. Am J Clin Dermatol. 2018;19:87-101 pubmed publisher
    ..In this article, the skin lesions associated with this condition are reviewed, lung and renal manifestations associated with this syndrome are presented, and malignancies occurring in these patients are summarized. ..
  27. Udkoff J, Cohen P. Tumor necrosis factor-induced alopecia: alternative pathology and therapy. Dermatol Online J. 2017;23: pubmed
    ..In conclusion, various histopathologies are observed with TNF-inhibitor induced alopecia and multiple, effective, therapeutic avenues exist for this affliction. ..
  28. Stiff K, Cohen P. Cutaneous varicella zoster virus infection following zoster vaccination: report of post-vaccination herpes zoster skin infection and literature review of zoster vaccination efficacy and guidelines. Dermatol Online J. 2017;23: pubmed
    ..ConclusionsHerpes zoster vaccine decreases in efficacy with both age and number of years following vaccination. Therefore, booster shots or revaccination in the older population may be of benefit. ..
  29. Bari O, Cohen P. Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. Dermatol Ther (Heidelb). 2017;7:203-210 pubmed publisher
    ..Prompt response to mupirocin 2% ointment is highly suggestive of the diagnosis of BCP since morphologically similar skin conditions do not respond to this treatment. ..
  30. Cohen P. Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor. Med Hypotheses. 2017;101:1-5 pubmed publisher
    ..The vascular endothelial growth factor inhibitor would be bevacizumab. In conclusion, a novel-topically administered-therapy for melasma would combine an anti-estrogen and a vascular endothelial growth factor inhibitor. ..