Xin Chen


Affiliation: Nanjing Medical University
Country: China


  1. Li L, Wang X, Chen W, Qi H, Jiang D, Huang L, et al. Regulatory role of CARD3 in left ventricular remodelling and dysfunction after myocardial infarction. Basic Res Cardiol. 2015;110:56 pubmed publisher
    ..Thus, CARD3 may be a promising therapeutic target for the treatment of heart failure after MI. ..
  2. Liu S, Iskandar R, Chen W, Zhang J, Wang Y, Chen X, et al. Soluble Glycoprotein 130 and Heat Shock Protein 27 as Novel Candidate Biomarkers of Chronic Heart Failure with Preserved Ejection Fraction. Heart Lung Circ. 2016;25:1000-6 pubmed publisher
    ..882, respectively. Soluble glycoprotein 130 and hsp27 are novel candidate biomarkers for diagnosing CHF with preserved ejection fraction and thus warrant further investigation; neither dpp4 nor CTSS showed promise as biomarkers of CHF. ..
  3. Li L, Chen W, Zhu Y, Wang X, Jiang D, Huang F, et al. Caspase recruitment domain 6 protects against cardiac hypertrophy in response to pressure overload. Hypertension. 2014;64:94-102 pubmed publisher
    ..Thus, our study suggests that CARD6 may be a novel target for the treatment of pathological cardiac hypertrophy and failure. ..
  4. Huang F, Li L, Qin W, Su C, Wang L, Xiao L, et al. Partial aortic root remodeling for root reconstruction in patients with acute type A dissection. J Biomed Res. 2016;30:411-418 pubmed publisher
    ..Thus, the use of technique for root reconstruction in patients with acute type A dissection should be vigorously encouraged. ..
  5. Zhang L, Chen W, Xu Y, Wang L, Iskandar R, Wang Y, et al. The expression of inhibitor of nuclear factor kappa-B kinase epsilon (IKKe) in human aortic aneurysm. Folia Morphol (Warsz). 2017;76:372-378 pubmed publisher
    ..The over-expression of IKKe may play an important role in the ori-gination and progression of AA and might be a vital target for their treatment. ..
  6. Wang X, Chen W, Zhang J, Khan A, Li L, Huang F, et al. Critical Role of ADAMTS2 (A Disintegrin and Metalloproteinase With Thrombospondin Motifs 2) in Cardiac Hypertrophy Induced by Pressure Overload. Hypertension. 2017;69:1060-1069 pubmed publisher
    ..Because ADAMTS2 is an extracellular protein, it could be effectively manipulated using pharmacological means to modulate cardiac hypertrophy. ..
  7. Chai H, Tao Z, Chen W, Xu Y, Huang F, Su C, et al. Cortistatin attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the ERK1/2 signaling pathways. Biochem Biophys Res Commun. 2018;495:1801-1806 pubmed publisher
    ..In conclusion, cortistatin appears to play an essential role in the formation of AAA and indicate cortistatin may as novel therapeutic option for AAA. ..

Detail Information