Fang C, Li S, Xu R, Guo H, Jiang R, Ding S, et al
. Soluble B7-H3 (sB7-H3) is over-expressed in the serum of type 1 diabetes patients. Diabetes Res Clin Pract. 2018;: pubmed publisher
..We demonstrated increased level of sB7-H3 in T1D patients than in healthy control group. This result suggests that B7-H3 may be may be a promising biomarker associated with the athogenesis of T1D . ..
Hu X, Wu J, An J, Hu Y, Shen Y, Liu C, et al
. Development of a novel monoclonal antibody to human inducible co-stimulator ligand (ICOSL): Biological characteristics and application for enzyme-linked immunosorbent assay. Int Immunopharmacol. 2016;36:151-157 pubmed publisher
..Together, these data demonstrate that the existence of circulating sICOSL in human serum might play an important role in immunoregulation. ..
Jiang J, Liu C, Liu M, Shen Y, Hu X, Wang Q, et al
. OX40 signaling is involved in the autoactivation of CD4+CD28- T cells and contributes to the pathogenesis of autoimmune arthritis. Arthritis Res Ther. 2017;19:67 pubmed publisher
..OX40 acts as an alternative costimulator of CD4+CD28- T cells and plays a pathogenic role in autoimmune arthritic development, suggesting that it is a potential target for immunomodulatory therapy of RA. ..