Affiliation: Faculty of Science
- Nyasse B, Nkwengoua E, Sondengam B, Denier C, Willson M. Modified berberine and protoberberines from Enantia chlorantha as potential inhibitors of Trypanosoma brucei. Pharmazie. 2002;57:358-61 pubmed..The inhibitory activities observed were in the range of 20 microM (ED50 values). ..
- Nyasse B, Ngantchou I, Tchana E, Sonke B, Denier C, Fontaine C. Inhibition of both Trypanosoma brucei bloodstream form and related glycolytic enzymes by a new kolavic acid derivative isolated from Entada abyssinica. Pharmazie. 2004;59:873-5 pubmed..The new derivative showed a strong and selective inhibitory activity on the GAPDH enzyme of Trypanosoma brucei with an IC50 value of 0.012 mM. ..
- Nyasse B, Ngantchou I, Nono J, Schneider B. Antifilarial activity in vitro of polycarpol and 3-O-acetyl aleuritolic acid from cameroonian medicinal plants against Onchocerca gutturosa. Nat Prod Res. 2006;20:391-7 pubmed..gutturosa using Amocarzine as positive control compound. The motility reduction values were 28.6 and 57.1%, and the inhibition of MTT reduction values 80.0 and 64.8% respectively. ..