Martyn A French
Affiliation: University of Western Australia
Tjiam M, Taylor J, Morshidi M, Sariputra L, Burrows S, Martin J, et al
. Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell-Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype Diversification. J Immunol. 2015;194:5320-8 pubmed publisher
French M, Abudulai L, Fernandez S. Isotype Diversification of IgG Antibodies to HIV Gag Proteins as a Therapeutic Vaccination Strategy for HIV Infection. Vaccines (Basel). 2013;1:328-42 pubmed publisher
..We suggest that this should be investigated as a vaccination strategy for HIV-1 infection. ..
Sojane K, Kangethe R, Chang C, Moosa M, LEWIN S, French M, et al
. Individuals with HIV-1 subtype C infection and cryptococcal meningitis exhibit viral genetic intermixing of HIV-1 between plasma and cerebrospinal fluid, and a high prevalence of CXCR4-using variants. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
French M, Tanaskovic S, Law M, Lim A, Fernandez S, Ward L, et al
. Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a 'high-affinity' FcgammaRIIa genotype. AIDS. 2010;24:1983-90 pubmed publisher
..The role of IgG2 anti-HIV antibodies and FcgammaRIIa in the control of HIV replication should be investigated further. Inclusion of an IFN-gamma gene in DNA vaccine constructs might be a means of enhancing IgG2 antibody production. ..
French M. Immune reconstitution inflammatory syndrome: immune restoration disease 20 years on. Med J Aust. 2012;196:318-21 pubmed
..A greater understanding of the immunopathogenesis of IRIS may lead to targeted therapies. ..
French M, Center R, Wilson K, Fleyfel I, Fernandez S, Schorcht A, et al
. Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers. AIDS. 2013;27:519-28 pubmed publisher
..We hypothesize that isotype-switched (IgG2+) antibodies to HIV Gag proteins and possibly IgG1 antip32 may provide alternative or additional immune control mechanisms to HLA-restricted CD8 T-cell responses in HIV controllers. ..
McCloskey J, Kast W, Flexman J, McCallum D, French M, Phillips M. Syndemic synergy of HPV and other sexually transmitted pathogens in the development of high-grade anal squamous intraepithelial lesions. Papillomavirus Res. 2017;4:90-98 pubmed publisher
..This pattern of disease in patients with warts is characteristic of a syndemic with potential serious increased risk of anal carcinoma. ..