Denham M, Bye C, Leung J, Conley B, Thompson L, Dottori M. Glycogen synthase kinase 3? and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage. Stem Cells. 2012;30:2400-11 pubmed publisher
Denham M, Thompson L, Leung J, Pebay A, Bjorklund A, Dottori M. Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells. Stem Cells. 2010;28:1805-15 pubmed publisher
..This study demonstrates that GLI1 is a determinant of FP specification in hESC and describes a highly robust and efficient in vitro model system that mimics the ventral neural tube organizer. ..