Wy Au



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    Au W, Ma S, Yeung C, Chan H, Trendell Smith N. A patient with congenital ichthyosis hystrix (disseminated congenital naevus) and acute lymphoblastic leukaemia. Leuk Lymphoma. 2003;44:209-12 pubmed
    ..There are four reports of acute leukaemia complicating ichthyosis, all involving paediatric acute lymphoblastic leukaemia. The possible mechanisms involved are discussed. ..
  2. Au W, Lam W, Chu W, Tam S, Wong W, Chan H, et al. A pilot MRI study of organ specific hemosiderosis and functional correlation in Chinese patients with myelodysplasia and aplastic anemia with raised ferritin levels. Hematol Oncol. 2008;26:225-8 pubmed publisher
    ..Hence, chelating agents may still have a role to improve organ function. Prospective data with serial functional and imaging monitoring is needed. ..
  3. Au W, Lam W, Chu W, Tam S, Wong W, Lau J, et al. Organ-specific hemosiderosis and functional correlation in Chinese patients with thalassemia intermedia and hemoglobin H disease. Ann Hematol. 2009;88:947-50 pubmed publisher
    ..Prospective data with serial functional and imaging monitoring is needed to verify the utility for chelation to improve cardiac and endocrine function in this group of patients. ..
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    Au W, Horsman D, Gascoyne R, Viswanatha D, Klasa R, Connors J. The spectrum of lymphoma with 8q24 aberrations: a clinical, pathological and cytogenetic study of 87 consecutive cases. Leuk Lymphoma. 2004;45:519-28 pubmed
    ..We conclude that the finding of an 8q24 aberration is of marked negative prognostic significance, either at diagnosis or at disease progression, in a variety of NHL. ..
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    Au W, Ooi G, Ma S, Wan T, Kwong Y. Chronic myeloid leukemia in an adolescent with Ollier's disease after intensive X-ray exposure. Leuk Lymphoma. 2004;45:613-6 pubmed
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    Au W, Lam W, Chu W, Tam S, Wong W, Pennell D, et al. A magnetic resonance imaging study of iron overload in hemopoietic stem cell transplant recipients with increased ferritin levels. Transplant Proc. 2007;39:3369-74 pubmed
    ..We concluded that iron overload may contribute to organ damage after HSCT, and MRI assessment may be useful in its detection and treatment monitoring. ..
  7. Au W, Lam W, Chu W, Tam S, Wong W, Liang R, et al. A T2* magnetic resonance imaging study of pancreatic iron overload in thalassemia major. Haematologica. 2008;93:116-9 pubmed publisher
    ..This suggested that improved chelation may improve beta cell reserve and prevent pancreatic atrophy. ..
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    Au W, Lee V, Lau C, Yau J, Chan D, Chan E, et al. A synopsis of current care of thalassaemia major patients in Hong Kong. Hong Kong Med J. 2011;17:261-6 pubmed
    ..The future for thalassaemia care in Hong Kong is bright. With better transfusion and chelation, it should be possible to avoid growth and endocrine deficiencies in younger patients. ..
  9. Au W, Wong K, Leung R, Tong A. Isolated gingival relapse of acute lymphoblastic leukemia after transplantation. J Oral Pathol Med. 2008;37:249-51 pubmed publisher
    ..Examinations of the peripheral blood and marrow were normal. Molecular studies confirmed clonal relationship between the gum lesion with the original marrow disease, despite the anatomical, histological and chronological separations. ..

More Information


  1. Au W, Wong K, Wan T, So J, Srivastava G, Liang R. A unique case of B cell lymphoma relapsing as CD4/CD56 blastic neoplasm. Leuk Lymphoma. 2009;50:932-6 pubmed publisher
    ..Our case illustrated the potential pitfalls and ambiguity of lineage classification based on morphology and immunophenotyping alone, especially for rare and poorly defined entities. ..
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    Au W, Ma S, Wan T, Jim M, Kwong Y. Subvalvular pulmonary stenosis, demyelination and myelodysplasia with monosomy 7. Leuk Lymphoma. 2002;43:1505-7 pubmed
    ..The importance of recognition of rare clinical syndromes that may predispose to leukemia is discussed. ..
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    Au W, Ma S, Kwong Y. Disseminated hepatosplenic mycobacterial infection masking myeloproliferative diseases as leukemoid reaction: a diagnostic pitfall. Leuk Lymphoma. 2001;42:805-8 pubmed
    ..Clinicians and hematologist should be aware of such a predisposition and possible dual pathology for proper diagnosis, therapy and monitoring of both the infection and the myeloproliferation...
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    Au W, Hon C, Lie A, Yeung C, Ma S, Chan H. Keratoderma blenorrhagica, balanitis and uveitis after HLA-B15 mismatched bone marrow transplantation. Haematologica. 2002;87:ECR10 pubmed
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    Au W, Cheung W, Hu W, Chan G, Ha S, Khong P, et al. Hyperbilirubinemia and cholelithiasis in Chinese patients with hemoglobin H disease. Ann Hematol. 2005;84:671-4 pubmed
    ..2%), but not heterozgyotes (42.2%), were found to have a significantly increased risk of gallstones and jaundice. However, common Chinese Gilbert syndrome alleles do not completely explain the variable risks...